LEADER 05617nam 22007215 450 001 9910298291103321 005 20200705013605.0 010 $a1-4939-1935-0 024 7 $a10.1007/978-1-4939-1935-2 035 $a(CKB)3710000000315714 035 $a(EBL)1968310 035 $a(SSID)ssj0001407875 035 $a(PQKBManifestationID)11818644 035 $a(PQKBTitleCode)TC0001407875 035 $a(PQKBWorkID)11411409 035 $a(PQKB)10714166 035 $a(DE-He213)978-1-4939-1935-2 035 $a(MiAaPQ)EBC1968310 035 $a(PPN)183154185 035 $a(EXLCZ)993710000000315714 100 $a20141210d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aStudies on the Cornea and Lens /$fedited by Mark A. Babizhayev, David Wan-Cheng Li, Anne Kasus-Jacobi, Lep?a ?ori?, Jorge L. Alió 205 $a1st ed. 2015. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Humana,$d2015. 215 $a1 online resource (450 p.) 225 1 $aOxidative Stress in Applied Basic Research and Clinical Practice,$x2197-7224 300 $aDescription based upon print version of record. 311 $a1-4939-1934-2 320 $aIncludes bibliographical references and index. 327 $a1 Oxidative Stress in Cornea -- 2 Corneal Degenerations -- 3 Corneal Epithelial Nuclear Ferritin and its Transporter Ferritoid Afford Unique Protection to DNA from U.V. Light and Reactive Oxygen Species -- 4 Excitatory Amino Acid Transporters, Xc- Antiporter, Glutamyl Transpeptidase, Glutamine Synthetase Activity and Glutathione in Human Corneal Epithelial Cells -- 5 Transforming Growth Factor ? ?3 Regulates Cell Metabolism in Corneal Keratocytes and Fibroblasts -- 6 Corneal Stem Cells: a Source of Cell Renewal with Therapeutic Potential -- 7 New Agents for Treating Dry Eye Syndrome -- 8 Investigating Carcinine Transport and the Expression Profile of Transporter Genes in Human Corneal Epithelial Cells -- 9 Basic Review of the Oxidative Stress Role in Age-Related Cataractogenesis -- 10 The Human Lens: A living Biometric Indicator of Health Status and Successful Aging -- 11 Oxidative Stress in Lens -- 12 Protein Serine/Threonine Phosphatases-1 and ?2A in Lens Development and Pathogenesis -- 13 Proteases in Lens and Cataract -- 14 Photosensitized Oxidation of Lens Proteins Exposed to UVA-Visible Light at Low Oxygen Concentration: Its Effect on the Proteasome System -- 15 p53 Regulates Developmental Apoptosis and Gene Expression to Modulate Lens Differentiation -- 16 Etiology and Prevention of Cataract -- 17 The Effects of Lutein in Preventing Cataract Progression -- 18 Antioxidant Defense Network in the Lens and Benefits of Glutathione Prodrugs in Cataracts -- 19 Updates and Advanc es in Corneal Surgery -- 20 Cataract and Diabetic Retinopathy -- 21 Traumatic Cataract-a Review -- 22 Cataract in Paediatric Age Group-a Review. 330 $aThis comprehensive volume presents data describing the role of oxidative stress in anterior eye disease. The content is divided into three logical parts: basic science of the cornea, basic science of the lens, and clinical practices. The first two parts include eighteen chapters that discuss topics ranging from oxidative stress and dry eye disease, endogenous protection of corneal cells against oxidative damage, the therapeutic potential of corneal stem cells, etiology of cataracts and preventive measures, corneal degeneration through oxidative stress and cataract formation, and function and dysregulation of ion channels and transporters in the ocular lens, among others. The concluding part is comprised of four chapters devoted to advancements in corneal surgery, cataract and diabetic retinopathy, the clinical treatment of cataracts including traumatic cataracts, and cataracts in the pediatric age group. Studies on the Cornea and Lens is an essential addition to the library or department of physicians and scientists who treat or research these ocular conditions, particularly cataracts. It is also a key resource for cell biologists studying oxidative stress. This book is an authoritative contribution to Springer?s Oxidative Stress in Applied Basic Research and Clinical Practice series. 410 0$aOxidative Stress in Applied Basic Research and Clinical Practice,$x2197-7224 606 $aOxidative stress 606 $aOphthalmology 606 $aApoptosis 606 $aOxidative Stress$3https://scigraph.springernature.com/ontologies/product-market-codes/L16070 606 $aOphthalmology$3https://scigraph.springernature.com/ontologies/product-market-codes/H44004 606 $aApoptosis$3https://scigraph.springernature.com/ontologies/product-market-codes/L16060 615 0$aOxidative stress. 615 0$aOphthalmology. 615 0$aApoptosis. 615 14$aOxidative Stress. 615 24$aOphthalmology. 615 24$aApoptosis. 676 $a617.7 676 $a617.719 702 $aBabizhayev$b Mark A$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aLi$b David Wan-Cheng$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKasus-Jacobi$b Anne$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $a?ori?$b Lep?a$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aAlió$b Jorge L$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298291103321 996 $aStudies on the Cornea and Lens$92508856 997 $aUNINA