LEADER 03771nam 22007575 450 001 9910298289703321 005 20200701061350.0 010 $a3-319-12298-3 024 7 $a10.1007/978-3-319-12298-4 035 $a(CKB)3710000000291644 035 $a(EBL)1967380 035 $a(OCoLC)897115936 035 $a(SSID)ssj0001385852 035 $a(PQKBManifestationID)11895245 035 $a(PQKBTitleCode)TC0001385852 035 $a(PQKBWorkID)11348914 035 $a(PQKB)10433589 035 $a(DE-He213)978-3-319-12298-4 035 $a(MiAaPQ)EBC1967380 035 $a(PPN)183094166 035 $a(EXLCZ)993710000000291644 100 $a20141125d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe NeuroMuscular System: From Earth to Space Life Science $eNeuromuscular Cell Signalling in Disuse and Exercise /$fby Dieter Blottner, Michele Salanova 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (105 p.) 225 1 $aSpringerBriefs in Space Life Sciences,$x2196-5560 ;$v0 300 $aDescription based upon print version of record. 311 $a3-319-12297-5 320 $aIncludes bibliographical references at the end of each chapters. 327 $aGeneral Introduction -- Skeletal Muscle -- Neuromuscular System -- Physical Countermeasure in Space: Efforts in Vain? 330 $aThe book provides fundamental new insights in the structure and function of the healthy  NeuroMuscular system. Recent findings suggest that the musculoskeletal system that supports movement control on Earth is controlled by unique principles of structural, biochemical and molecular characteristics. Mechanical loading by working against normal gravity helps to support principal structures in bone, muscle and associated subcellular scaffold components. Disuse or immobilization of the body in bed rest on Earth or in microgravity in Space result in considerable loss of bone, muscle and force with downregulation of neuromuscular activity resulting in impaired performance control. The goal is to develop exercise prescriptions to maintain postural control in normal life, aging and rehabilitation on Earth as well as for an adequate human performance management in Space. 410 0$aSpringerBriefs in Space Life Sciences,$x2196-5560 ;$v0 606 $aHuman physiology 606 $aAerospace engineering 606 $aAstronautics 606 $aNeurosciences 606 $aHuman anatomy 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 606 $aAerospace Technology and Astronautics$3https://scigraph.springernature.com/ontologies/product-market-codes/T17050 606 $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006 606 $aAnatomy$3https://scigraph.springernature.com/ontologies/product-market-codes/H12005 615 0$aHuman physiology. 615 0$aAerospace engineering. 615 0$aAstronautics. 615 0$aNeurosciences. 615 0$aHuman anatomy. 615 14$aHuman Physiology. 615 24$aAerospace Technology and Astronautics. 615 24$aNeurosciences. 615 24$aAnatomy. 676 $a591.1 700 $aBlottner$b Dieter$4aut$4http://id.loc.gov/vocabulary/relators/aut$01057736 702 $aSalanova$b Michele$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298289703321 996 $aThe NeuroMuscular System: From Earth to Space Life Science$92494361 997 $aUNINA