LEADER 02368oam 2200385z- 450 001 9910157428803321 005 20160407085119.0 010 $a9780745685687 010 $a0745685684 035 $a(CKB)3810000000069025 035 $a(VLeBooks)9780745685687 035 $a(Perlego)1535735 035 $a(EXLCZ)993810000000069025 100 $a20200619d2015 uy | 101 0 $aeng 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aIran at the Crossroads 210 $cPolity 215 $a1 online resource (138 p.) 311 08$a9780745685656 311 08$a074568565X 311 08$a9780745685649 311 08$a0745685641 327 $aIntroduction -- From Empire to Islamic Republic -- The Islamic Order -- Rouhani's Presidency and US-Iranian Relations -- The Complex Road Ahead -- Conclusion. 330 $a Iran stands at a critical juncture in its history. In the era of Presidents Hassan Rouhani and Barack Obama, the Islamic Republic has a unique opportunity to regain its traditional greatness as a cradle of rich civilisation and culture, with a capacity to be a very influential and stabilising regional actor. In this incisive analysis, Amin Saikal, a leading expert on Iranian politics, traces Iran's transition from pro-Western monarchy to Islamic Republic and explores the choices open to Rouhani's moderate reformist government. The Islamic Republic has endured a difficult journey throughout its existence. But since Khomeini assumed power in 1979 it has been characterised by a degree of exceptionalism, which has seen Iran lock horns with the United States and prove itself an effective and shrewdly calculating player on the international stage. Looking to the future, Saikal does not shy away from confronting the difficult choices facing Iran today. Failure to achieve reconciliation with the United States in the coming years, he argues, will not only have serious implications for Iran's internal stability and for the future security of the Middle East, but also for America's position within this volatile and unpredictable region. 606 $aIslam and state 615 0$aIslam and state. 676 $a955.054 700 $aSaikal$b Amin$0561830 906 $aBOOK 912 $a9910157428803321 996 $aIran at the Crossroads$94176801 997 $aUNINA LEADER 04354nam 22007815 450 001 9910298288303321 005 20251116135925.0 010 $a3-662-44287-6 024 7 $a10.1007/978-3-662-44287-6 035 $a(CKB)3710000000305964 035 $a(EBL)1965953 035 $a(SSID)ssj0001385831 035 $a(PQKBManifestationID)11746770 035 $a(PQKBTitleCode)TC0001385831 035 $a(PQKBWorkID)11358697 035 $a(PQKB)11646825 035 $a(DE-He213)978-3-662-44287-6 035 $a(MiAaPQ)EBC1965953 035 $a(PPN)183087925 035 $a(EXLCZ)993710000000305964 100 $a20141129d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aGenetics of the Mouse /$fby Jean Louis Guénet, Fernando Benavides, Jean-Jacques Panthier, Xavier Montagutelli 205 $a1st ed. 2015. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2015. 215 $a1 online resource (417 p.) 300 $aDescription based upon print version of record. 311 08$a3-662-44286-8 320 $aIncludes bibliographical references. 327 $aOrigins of the Laboratory Mouse -- Basic Concepts of Reproductive Biology And Genetics -- Cytogenetics -- Gene Mapping -- The Mouse Genome -- Epigenetic Control of Genome Expression -- Mutations and Experimental Mutagenesis -- Transgenesis and Transgenic Animals -- The Different Categories of Genetically Standardized Populations of Laboratory Mice -- Quantitative Traits and Quantitative Genetics. 330 $aThis book, written by experienced geneticists, covers topics ranging from the natural history of the mouse species, its handling and reproduction in the laboratory, and its classical genetics and cytogenetics, to modern issues including the analysis of the transcriptome, the parental imprinting and X-chromosome inactivation. The strategies for creating all sorts of mutations, either by genetic engineering or by using mutagens, are also reviewed and discussed in detail. Finally, a last chapter outlines the methodology used for the analysis of complex or quantitative traits.   The authors also discuss the importance of accurate phenotyping, which is now performed in the mouse clinics established worldwide and identify the limits of the mouse model, which under certain circumstances can fail to present the phenotype expected from the cognate condition in the human model. For each chapter an up-to-date list of pertinent references is provided.   In short, this book offers an essential resource for all scientists who use or plan to use mice in their research. 606 $aAnimal genetics 606 $aAnimal models in research 606 $aTransgenic organisms 606 $aGene expression 606 $aGenetic engineering 606 $aAnimal Genetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32030 606 $aAnimal Models$3https://scigraph.springernature.com/ontologies/product-market-codes/L25050 606 $aTransgenics$3https://scigraph.springernature.com/ontologies/product-market-codes/L25025 606 $aGene Expression$3https://scigraph.springernature.com/ontologies/product-market-codes/B12010 606 $aGenetic Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/C12037 615 0$aAnimal genetics. 615 0$aAnimal models in research. 615 0$aTransgenic organisms. 615 0$aGene expression. 615 0$aGenetic engineering. 615 14$aAnimal Genetics and Genomics. 615 24$aAnimal Models. 615 24$aTransgenics. 615 24$aGene Expression. 615 24$aGenetic Engineering. 676 $a570 676 $a591.35 676 $a611.01816 676 $a616.027 676 $a660.65 700 $aGue?net$b Jean Louis$4aut$4http://id.loc.gov/vocabulary/relators/aut$01058334 702 $aBenavides$b Fernando$4aut$4http://id.loc.gov/vocabulary/relators/aut 702 $aPanthier$b Jean-Jacques$4aut$4http://id.loc.gov/vocabulary/relators/aut 702 $aMontagutelli$b Xavier$4aut$4http://id.loc.gov/vocabulary/relators/aut 906 $aBOOK 912 $a9910298288303321 996 $aGenetics of the Mouse$92499289 997 $aUNINA