LEADER 04345nam  22008175  450 
001 9910298279503321
005 20200703024620.0
010   $a4-431-54385-6
024 7 $a10.1007/978-4-431-54385-5
035   $a(CKB)3710000000412280
035   $a(EBL)2093698
035   $a(SSID)ssj0001500681
035   $a(PQKBManifestationID)11874349
035   $a(PQKBTitleCode)TC0001500681
035   $a(PQKBWorkID)11519887
035   $a(PQKB)11339526
035   $a(DE-He213)978-4-431-54385-5
035   $a(MiAaPQ)EBC2093698
035   $a(PPN)186024681
035   $a(EXLCZ)993710000000412280
100   $a20150507d2015      u|             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aSemaphorins$b[electronic resource] $eA Diversity of Emerging Physiological and Pathological Activities /$fedited by Atsushi Kumanogoh
205   $a1st ed. 2015.
210  1$aTokyo :$cSpringer Japan :$cImprint: Springer,$d2015.
215   $a1 online resource (225 p.)
300   $aDescription based upon print version of record.
311   $a4-431-54384-8 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $a1. Semaphorin Receptors and their Signaling -- 2. Semaphorin Regulation of Neural Circuit Assembly in the Central Nervous System -- 3. Axon Guidance in the Spinal Cord -- 4. Semaphorin and Neuronal Migration in the Central Nervous System -- 5. Structure of Semaphorins and their Receptors -- 6. Regulation of Angiogenesis and Tumor Progression by Semaphorins -- 7. Semaphorins in the Immune System -- 8. Semaphorins in Bone Homeostasis -- 9. Semaphorin in the Heart -- 10. Semaphorins and Neurodegenerative Disorders -- 11. Semaphorin in the Retinal System.
330   $aThis book presents the current concepts of semaphorin biology. In the early 1990s, semaphorins were originally identified as axon guidance cues that function during neuronal development. However, cumulative findings have clarified that they have diverse functions in many physiological processes, including cardiogenesis, angiogenesis, vasculogenesis, osteoclastogenesis, retinal homeostasis, and immune regulation. Additionally, they have been implicated in the pathogenesis of various human diseases, including tumorigenesis/tumor metastasis, neuroregenerative diseases, retinal degeneration, irregular pulse/sudden death, and immune disorders. Based on this current research background, the book covers the essential state-of-the-art findings for basic scientists in biochemistry, molecular biology, neuroscience, developmental biology, and structural biology, as well as for physicians in neurology, cardiology, oncology, orthopedic surgery, otorhinolaryngology, ophthalmology, allergology, and rheumatology.
606   $aImmunology
606   $aNeurobiology
606   $aCancer research
606   $aCell biology
606   $aAngiology
606   $aMolecular biology
606   $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000
606   $aNeurobiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L25066
606   $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001
606   $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008
606   $aAngiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33010
606   $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X
615  0$aImmunology.
615  0$aNeurobiology.
615  0$aCancer research.
615  0$aCell biology.
615  0$aAngiology.
615  0$aMolecular biology.
615 14$aImmunology.
615 24$aNeurobiology.
615 24$aCancer Research.
615 24$aCell Biology.
615 24$aAngiology.
615 24$aMolecular Medicine.
676   $a571.6
676   $a573.8
676   $a610
676   $a611.01816
676   $a614.5999
676   $a616.13
676   $a616079
702   $aKumanogoh$b Atsushi$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298279503321
996   $aSemaphorins$92541198
997   $aUNINA