LEADER 04594nam 22007455 450 001 9910298278803321 005 20200704052332.0 010 $a3-319-11158-2 024 7 $a10.1007/978-3-319-11158-2 035 $a(CKB)3710000000277587 035 $a(EBL)1966779 035 $a(SSID)ssj0001385838 035 $a(PQKBManifestationID)11895243 035 $a(PQKBTitleCode)TC0001385838 035 $a(PQKBWorkID)11349475 035 $a(PQKB)11468772 035 $a(DE-He213)978-3-319-11158-2 035 $a(MiAaPQ)EBC1966779 035 $a(PPN)183095731 035 $a(EXLCZ)993710000000277587 100 $a20141106d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aInfluenza Pathogenesis and Control - Volume II$b[electronic resource] /$fedited by Michael B. A. Oldstone, Richard W. Compans 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (478 p.) 225 1 $aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v386 300 $aDescription based upon print version of record. 311 $a3-319-11157-4 320 $aIncludes bibliographical references and index. 327 $aThe role of cytokine responses during influenza virus pathogenesis and potential therapeutic options -- Innate immune sensing and response to influenza -- The NS1 protein: a multitasking virulence factor -- Role of NK cells in influenza infection -- Host detection and the stealthy phenotype in influenza virus infection -- Inactivated and adjuvanted influenza vaccines -- Live attenuated influenza vaccine -- Design of alternative live attenuated influenza virus vaccines -- Rapid production of synthetic influenza vaccines -- Influenza neuraminidase as a vaccine antigen -- Advances in universal influenza virus vaccine design and antibody mediated therapies based on conserved regions of the hemagglutinin -- Structural characterization of epitopes recognized by broadly cross-reactive antibodies -- Skin immunization with influenza vaccines -- Mucosal immunization and adjuvants -- B cell responses to infection and vaccination -- Memory CD4 T cells in influenza -- The effector T cell response to influenza infection -- Antiviral Effects of Inhibiting Host Gene Expression.   . 330 $aThis two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.  . 410 0$aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v386 606 $aImmunology 606 $aVaccines 606 $aInfectious diseases 606 $aHealth promotion 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aVaccine$3https://scigraph.springernature.com/ontologies/product-market-codes/B16010 606 $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096 606 $aHealth Promotion and Disease Prevention$3https://scigraph.springernature.com/ontologies/product-market-codes/H27010 615 0$aImmunology. 615 0$aVaccines. 615 0$aInfectious diseases. 615 0$aHealth promotion. 615 14$aImmunology. 615 24$aVaccine. 615 24$aInfectious Diseases. 615 24$aHealth Promotion and Disease Prevention. 676 $a610 676 $a613 676 $a614.44 676 $a615372 676 $a616.9 676 $a616079 702 $aOldstone$b Michael B. A$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aCompans$b Richard W$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298278803321 996 $aInfluenza Pathogenesis and Control - Volume II$92513404 997 $aUNINA