LEADER 05265nam 22008535 450 001 9910298274603321 005 20200704115407.0 010 $a94-007-6404-9 024 7 $a10.1007/978-94-007-6404-0 035 $a(CKB)3710000000343590 035 $a(Springer)9789400764040 035 $a(MH)014293404-6 035 $a(SSID)ssj0001424590 035 $a(PQKBManifestationID)11960388 035 $a(PQKBTitleCode)TC0001424590 035 $a(PQKBWorkID)11367520 035 $a(PQKB)11037424 035 $a(DE-He213)978-94-007-6404-0 035 $a(MiAaPQ)EBC5591468 035 $a(PPN)183519469 035 $a(EXLCZ)993710000000343590 100 $a20150107d2015 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aScorpion Venoms /$fedited by P. Gopalakrishnakone, Lourival D. Possani, Elisabeth F. Schwartz, Ricardo C. Rodríguez de la Vega 205 $a1st ed. 2015. 210 1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2015. 215 $a1 online resource (XXV, 575 p. 115 illus., 92 illus. in color. eReference.)$conline resource 225 1 $aToxinology,$x2542-761X 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a94-007-6405-7 311 $a94-007-6403-0 330 $aScorpions have fascinated humans for a long time, ?rst and foremost because of the harm the sting of a few species could cause but also due to their unique natural history and for the many biologically active compounds found in their venoms. This volume of the Toxinology handbook series covers all those aspects. The subjects are divided into seven sections starting with an introduction to the general aspects of scorpion biology and ecology, followed by the description of the ?envenomation? pathophysiology, pharmacokinetics, and pharmacodynamics of venoms and their complex interactions with the immune system. The future of anti-scorpion venom therapy is then covered in two chapters dedicated to alternatives to the century-old techniques currently used to produce ?anti-venoms?. The next section presents a world tour of ?scorpionism? and dangerous scorpion species and their impact on human health. It is worth remembering that envenomation due to scorpion stings is a substantial health hazard in Asian, Middle Eastern, African, and Latin American countries, with over one million people stung by scorpions every year, resulting in more than 3,000 deaths. Species-centered overviews of ?scorpion venoms? are presented in the next section, after which a section details the two main types of ?scorpion toxins?. The last section covers high-throughput transcriptome and proteome screenings now known as ?venomics?.   This volume provides chapters that are accessible to a broad audience, yet also contains the depth of knowledge and detail which makes it of interest to experts in the field. Readers of this reference work will leave well informed on the current state of the art of scorpion venom research. 410 0$aToxinology,$x2542-761X 606 $aMedicine 606 $aPharmacology 606 $aPharmaceutical technology 606 $aLife sciences 606 $aBiochemistry 606 $aAnimal physiology 606 $aBiomedicine, general$3https://scigraph.springernature.com/ontologies/product-market-codes/B0000X 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 606 $aLife Sciences, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L00004 606 $aAnimal Biochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/L14013 606 $aAnimal Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L33030 615 0$aMedicine. 615 0$aPharmacology. 615 0$aPharmaceutical technology. 615 0$aLife sciences. 615 0$aBiochemistry. 615 0$aAnimal physiology. 615 14$aBiomedicine, general. 615 24$aPharmacology/Toxicology. 615 24$aPharmaceutical Sciences/Technology. 615 24$aLife Sciences, general. 615 24$aAnimal Biochemistry. 615 24$aAnimal Physiology. 676 $a615.9 702 $aGopalakrishnakone$b P$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aPossani$b Lourival D$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aF. Schwartz$b Elisabeth$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aRodríguez de la Vega$b Ricardo C$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298274603321 996 $aScorpion Venoms$92518694 997 $aUNINA 999 $aThis Record contains information from the Harvard Library Bibliographic Dataset, which is provided by the Harvard Library under its Bibliographic Dataset Use Terms and includes data made available by, among others the Library of Congress