LEADER 01147cam0-22004091i-450- 001 990002557340403321 005 20091105160009.0 010 $a9971-83-003-5 035 $a000255734 035 $aFED01000255734 035 $a(Aleph)000255734FED01 035 $a000255734 100 $a20030910d1980----km-y0itay50------ba 101 0 $aeng$cchi 102 $aSG 105 $ay-------001yy 200 1 $aLectures on differential geometry$fSu Buchin$gtranslated from chinese by K. G. Chang 210 $aSingapore$cWorld Scientific Publishing$d1980 215 $a149 p.$d23 cm 610 0 $aGeometria 610 0 $aGeometria differenziale e algebrica 610 0 $aGeometria descrittiva, analitica, differenziale 676 $a516 676 $a514 700 1$aBuchin,$bSu$045407 702 1$aChang,$bK. G. 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990002557340403321 952 $aMXXVI-B-15$b3390$fMAS 952 $a28-A-29$b1021$fMA1 952 $a12-085F$b11710$fFI1 959 $aMAS 959 $aMA1 959 $aFI1 996 $aLectures on differential geometry$9437047 997 $aUNINA LEADER 03584nam 22007575 450 001 9910298272103321 005 20230810184149.0 010 $a3-319-13725-5 024 7 $a10.1007/978-3-319-13725-4 035 $a(CKB)3710000000329733 035 $a(EBL)1966005 035 $a(OCoLC)900639416 035 $a(SSID)ssj0001424497 035 $a(PQKBManifestationID)11891907 035 $a(PQKBTitleCode)TC0001424497 035 $a(PQKBWorkID)11362919 035 $a(PQKB)10923311 035 $a(DE-He213)978-3-319-13725-4 035 $a(MiAaPQ)EBC1966005 035 $a(PPN)183520467 035 $a(EXLCZ)993710000000329733 100 $a20150102d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aIgE Antibodies: Generation and Function /$fedited by Juan J. Lafaille, Maria A. Curotto de Lafaille 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (157 p.) 225 1 $aCurrent Topics in Microbiology and Immunology,$x2196-9965 ;$v388 300 $aDescription based upon print version of record. 311 $a3-319-13724-7 320 $aIncludes bibliographical references and index. 327 $aBiology of IgE Production: IgE Cell Differentiation and the Memory of IgE Responses -- Molecular Mechanisms of IgE Class Switch Recombination -- Anti-IgE Therapy: Clinical Utility and Mechanistic Insights -- New Insights on the Signaling and Function of the High Affinity Receptor for IgE -- Helminth-Induced IgE and Protection Against Allergic Disorders -- IgE Immunotherapy Against Cancer. 330 $aThis volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike. 410 0$aCurrent Topics in Microbiology and Immunology,$x2196-9965 ;$v388 606 $aImmunospecificity 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aAllergy 606 $aParasitology 606 $aAdaptive Immunity 606 $aBiomedical Research 606 $aAllergology 606 $aParasitology 615 0$aImmunospecificity. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aAllergy. 615 0$aParasitology. 615 14$aAdaptive Immunity. 615 24$aBiomedical Research. 615 24$aAllergology. 615 24$aParasitology. 676 $a616.0795 702 $aLafaille$b Juan J$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aCurotto de Lafaille$b Maria A$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298272103321 996 $aIgE Antibodies: Generation and Function$92499272 997 $aUNINA