LEADER 03324nam 22006255 450 001 9910298269503321 005 20200701060829.0 010 $a3-319-22020-9 024 7 $a10.1007/978-3-319-22020-8 035 $a(CKB)3710000000526837 035 $a(EBL)4179372 035 $a(SSID)ssj0001583783 035 $a(PQKBManifestationID)16264411 035 $a(PQKBTitleCode)TC0001583783 035 $a(PQKBWorkID)14864561 035 $a(PQKB)11574521 035 $a(DE-He213)978-3-319-22020-8 035 $a(MiAaPQ)EBC4179372 035 $z(PPN)25886480X 035 $a(PPN)190524669 035 $a(EXLCZ)993710000000526837 100 $a20151126d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBreast Cancer Stem Cells & Therapy Resistance /$fby Phuc Van Pham 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (122 p.) 225 1 $aSpringerBriefs in Stem Cells,$x2192-8118 ;$v0 300 $aDescription based upon print version of record. 311 $a3-319-22019-5 320 $aIncludes bibliographical references and index. 327 $a1 Introduction to Breast Cancer -- 2 Stem Cells and Cancer Stem Cells -- 3 Breast Cancer Stem Cell Identification and Isolation -- 4 Breast Cancer Stem Cell Culture and Proliferation -- 5 Breast Cancer Stem Cell Properties -- 6 Targeting Breast Cancer Stem Cells -- 7 Breast Cancer Stem Cells and Circulating Tumor Cells -- 8 Conclusion. 330 $aThis volume thoroughly examines breast cancer stem cells (BCSCs), from basic definitions to techniques for identifying, isolating, culturing, and targeting BCSCs for therapy; there is additional focus on pre-clinical and clinical results. The text begins with a discussion of breast cancer, focusing especially on the limitations of current therapies in its treatment. The subsequent chapters introduce and compare stem cells and cancer stem cells, describe properties and isolation techniques of BCSCs, and examine BCSC-targeting approaches. The text concludes with a discussion of controversy surrounding the BCSC hypothesis and of future research directions. Breast Cancer Stem Cells & Therapy Resistance, part of the SpringerBriefs in Stem Cells series, provides a succinct yet comprehensive overview of BCSCs for advanced students, graduate students and researchers as well as those working with breast cancer or stem cells in a clinical setting. 410 0$aSpringerBriefs in Stem Cells,$x2192-8118 ;$v0 606 $aStem cells 606 $aCancer research 606 $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 615 0$aStem cells. 615 0$aCancer research. 615 14$aStem Cells. 615 24$aCancer Research. 676 $a616.99449 700 $aPham$b Phuc Van$4aut$4http://id.loc.gov/vocabulary/relators/aut$01061906 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298269503321 996 $aBreast Cancer Stem Cells & Therapy Resistance$92521360 997 $aUNINA