LEADER 04349nam 22005295 450 001 9910298262503321 005 20200704232107.0 010 $a3-319-20206-5 024 7 $a10.1007/978-3-319-20206-8 035 $a(CKB)3710000000486770 035 $a(EBL)4178313 035 $a(SSID)ssj0001583813 035 $a(PQKBManifestationID)16264278 035 $a(PQKBTitleCode)TC0001583813 035 $a(PQKBWorkID)14865155 035 $a(PQKB)10597155 035 $a(DE-He213)978-3-319-20206-8 035 $a(MiAaPQ)EBC4178313 035 $a(PPN)190517786 035 $a(EXLCZ)993710000000486770 100 $a20150919d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aExcipient Applications in Formulation Design and Drug Delivery /$fedited by Ajit S Narang, Sai H S. Boddu 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (700 p.) 300 $aDescription based upon print version of record. 311 08$aPrint version: Excipient applications in formulation design and drug delivery. Cham, Switzerland : Springer, c2015 xi, 681 pages 9783319202051 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aForward -- Excipient Applications in Formulation Design and Drug Delivery: An Introduction -- Drug Excipient Interactions -- Reactive Impurities in Excipients -- Reactive Impurities in PEG: A Case Study -- Impact of Excipient Interactions on Solid Dosage Form Stability -- Protein ? Surfactant Interactions at the Air-Water Interface -- Smart Polymers in Drug Delivery -- Tailoring the Oral Release of Drugs Using Polymeric Excipients -- Solid lipid excipients as matrix agents for sustained drug delivery -- Impact of Excipient Interactions on Drug Bioavailability from Solid Dosage Forms -- Biopolymers in Medical Implants -- Selection of Excipients Based on the Biopharmaceutics Classification System of Drugs -- Excipient Selection in Oral Solid Dosage Formulations Containing Moisture Sensitive Drugs -- Silicone excipients in pharmaceutical drug delivery applications -- Excipients that Facilitate Amorphous Drug Stabilization -- Excipients in Pediatric Formulations: Biopharmaceutical and Toxicological Considerations -- Role of Innovator Product Characterization in Generic Product Development -- Addressing Excipient Variability in Formulation Design and Drug Development -- Improved Polymer Functionality by Cross-linking with Glutaraldehyde to Achieve Controlled Drug Release -- Excipient Design by Co-processing for Direct Compression Applications -- Excipients and Non-medicinal Agents as Active Pharmaceutical Ingredients -- Drug Delivery Applications of Chitosan and its Derivatives. 330 $aIn recent years, emerging trends in the design and development of drug products have indicated ever greater need for integrated characterization of excipients and in-depth understanding of their roles in drug delivery applications. This book presents a concise summary of relevant scientific and mechanistic information that can aid the use of excipients in formulation design and drug delivery applications. Each chapter is contributed by chosen experts in their respective ?elds, which affords truly in-depth perspective into a spectrum of excipient-focused topics. This book captures current subjects of interest ? with the most up to date research updates ? in the field of pharmaceutical excipients. This includes areas of interest to the biopharmaceutical industry users, students, educators, excipient manufacturers, and regulatory bodies alike. 606 $aPharmaceutical technology 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 615 0$aPharmaceutical technology. 615 14$aPharmaceutical Sciences/Technology. 676 $a615.19003 676 $a610 702 $aNarang$b Ajit S$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aBoddu$b Sai H S$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298262503321 996 $aExcipient Applications in Formulation Design and Drug Delivery$92539262 997 $aUNINA