LEADER 04588 am 22009013u 450 001 9910279577503321 005 20230125200812.0 010 $a3-319-72790-7 024 7 $a10.1007/978-3-319-72790-5 035 $a(CKB)4100000002892214 035 $a(DE-He213)978-3-319-72790-5 035 $a(MiAaPQ)EBC5591507 035 $a(Au-PeEL)EBL5591507 035 $a(OCoLC)1076240124 035 $a(MiAaPQ)EBC6422812 035 $a(Au-PeEL)EBL6422812 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/56055 035 $a(PPN)225550989 035 $a(EXLCZ)994100000002892214 100 $a20180307d2017 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHormones, Metabolism and the Benefits of Exercise$b[electronic resource] /$fedited by Bruce Spiegelman 205 $a1st ed. 2017. 210 $cSpringer Nature$d2018 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (X, 102 p.) 225 1 $aResearch and Perspectives in Endocrine Interactions,$x1861-2253 311 $a3-319-72789-3 327 $aIntroduction -- Human brown adipose tissue plasticity: hormonal and environmental manipulation -- The energy sensor AMPK: Adaptations to exercise, nutritional and hormonal signals -- Plasma steroids and cardiorespiratory fitness response to regular exercise -- Sending the signal: Muscle glycogen availability as a regulator of training adaptation -- Optimized engagement of macrophages and satellite cells in the repair and regeneration of exercised muscle -- Skeletal muscle microRNAs: Roles in differentiation, disease and exercise -- Tryptophan-kynurenine metabolites in exercise and mental health -- FNDC5/irisin - their role in the nervous system and as a mediator for beneficial effects of exercise on the brain. 330 $aThe world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel ?myokines? that might act as new therapeutic agents in the future. 410 0$aResearch and Perspectives in Endocrine Interactions,$x1861-2253 606 $aMolecular biology 606 $aHealth promotion 606 $aEndocrinology  606 $aCardiology 606 $aDiabetes 606 $aMetabolic diseases 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 606 $aHealth Promotion and Disease Prevention$3https://scigraph.springernature.com/ontologies/product-market-codes/H27010 606 $aEndocrinology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33053 606 $aCardiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33037 606 $aDiabetes$3https://scigraph.springernature.com/ontologies/product-market-codes/H33045 606 $aMetabolic Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33118 610 $ahuman brown adipose tissue plasticity 610 $atype 2 diabetes 610 $aTryptophan-kynurenine metabolites 610 $ametabolic diseases 610 $amuscle glycogen 610 $aAMPK 610 $askeletal muscle microRNAs 610 $aFNDC5/irisin 610 $aobesity 615 0$aMolecular biology. 615 0$aHealth promotion. 615 0$aEndocrinology . 615 0$aCardiology. 615 0$aDiabetes. 615 0$aMetabolic diseases. 615 14$aMolecular Medicine. 615 24$aHealth Promotion and Disease Prevention. 615 24$aEndocrinology. 615 24$aCardiology. 615 24$aDiabetes. 615 24$aMetabolic Diseases. 676 $a611.01816 700 $aBruce Spiegelman$4auth$01356843 702 $aSpiegelman$b Bruce$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910279577503321 996 $aHormones, Metabolism and the Benefits of Exercise$93361762 997 $aUNINA