LEADER 03784nam 22005655 450 001 9910279574903321 005 20251113202850.0 010 $a3-662-47039-X 024 7 $a10.1007/978-3-662-47039-8 035 $a(CKB)3710000000501087 035 $a(EBL)4092230 035 $a(SSID)ssj0001585413 035 $a(PQKBManifestationID)16265572 035 $a(PQKBTitleCode)TC0001585413 035 $a(PQKBWorkID)14864775 035 $a(PQKB)10587887 035 $a(DE-He213)978-3-662-47039-8 035 $a(MiAaPQ)EBC4092230 035 $a(PPN)190516461 035 $a(EXLCZ)993710000000501087 100 $a20151103d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aPercutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement $eModification of the Stratum Corneum /$fedited by Nina Dragicevic, Howard I. Maibach 205 $a1st ed. 2015. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2015. 215 $a1 online resource (415 p.) 300 $aDescription based upon print version of record. 311 08$a3-662-47038-1 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aFrom the contents: THE ROLE OF SKIN HYDRATION IN PENETRATION ENHANCEMENT -- CHEMICAL PENETRATION ENHANCERS IN PENETRATION ENHANCEMENT.-Classification -- Mechanism -- Structure?Activity Relationship -- The Microenvironment Of The Enhancer Site Of Action -- Sulphoxides And Similar Chemicals -- Iminosulfuranes -- Azone  And Azone Analogues -- Fatty Acids, Fatty Acid Esters And Fatty Alcohols -- Alcohols And Glycols -- Terpenes And Essential Oils -- Transcutol Surfactants -- Nonionic Surfactants -- Natural Surfactants Of The Alkylpolyglucoside Type -- Sucrose Esters -- Pyrrolidones -- Chitosan -- Urea And Its Derivatives -- Transcarbams -- Amines And Amides -- Peptides -- Synergistic Effects -- CHEMICAL METHODS FOR TRANSDERMAL DELIVERY OF PEPTIDES AND PROTEINS -- Ultradeformable Vesicles -- Biphasic Vesicles For Transdermal Delivery Of Proteins -- CHEMICAL METHODS IN CUTANEOUS VACCINATION -- Vesicular Carriers In Transcutaneous DNA Vaccination -- Nanoparticles And Microparticles For Transcutaneous DNA Vaccination -- Chitosan-Nanoparticles In Gene Delivery. 330 $aPercutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods ? both well established and recently introduced ? in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered and the latest findings are provided on skin structure and function, mathematics in skin permeation and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners and also students. 606 $aDermatology 606 $aPharmacology 606 $aDermatology 606 $aPharmacology 615 0$aDermatology. 615 0$aPharmacology. 615 14$aDermatology. 615 24$aPharmacology. 676 $a610 702 $aDragicevic$b Nina$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMaibach$b Howard I$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910279574903321 996 $aPercutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement$92518556 997 $aUNINA