LEADER 03617oam 22007574a 450 001 9910272353203321 005 20230621141343.0 010 $a9781501726385 010 $a1501726382 010 $a9781501726392 010 $a1501726390 024 7 $a10.7591/9781501726392 035 $a(CKB)4340000000258208 035 $a(MiAaPQ)EBC5317514 035 $a(OCoLC)1057427496 035 $a(MdBmJHUP)muse67877 035 $a(DE-B1597)496622 035 $a(OCoLC)1028954219 035 $a(DE-B1597)9781501726392 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/89126 035 $a(Perlego)566075 035 $a(oapen)doab89126 035 $a(DE-B1597)BR1213978 035 $z(OCoLC)1028954219 035 $a(oapen)89126 035 $a(EXLCZ)994340000000258208 100 $a19920219d1992 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 14$aThe Anxiety of Freedom$eImagination and Individuality in Locke's Political Thought /$fUday Singh Mehta 210 $cCornell University Press$d2018 210 1$aIthaca, N.Y. :$cCornell University Press,$d1992. 210 4$dİ1992. 215 $a1 online resource (186 pages) 225 1 $aContestations 311 08$a9781501726385 311 08$a9780801427565 311 08$a0801427568 311 08$a9781501726408 311 08$a1501726404 320 $aIncludes bibliographical references (p. 175-181) and index. 327 $tFrontmatter --$tContents --$tAcknowledgments --$t1. Introduction --$t2. The Critique of Scriptural Politics --$t3. Curiosity, Imagination, and Madness --$t4. Molding Individuality: Direction and Compromise --$t5. Conclusion --$tBibliography --$tIndex 330 $aThe enduring appeal of liberalism lies in its commitment to the idea that human beings have a "natural" potential to live as free and equal individuals. The realization of this potential, however, is not a matter of nature, but requires that people be molded by a complex constellation of political and educational institutions. In this eloquent and provocative book, Uday Singh Mehta investigates in the major writings of John Locke the implications of this tension between individuals and the institutions that mold them. The process of molding, he demonstrates, involves an external conformity and an internal self-restraint that severely limit the scope of individuality.Mehta explores the centrality of the human imagination in Locke's thought, focusing on his obsession with the potential dangers of the cognitive realm. Underlying Locke's fears regarding the excesses of the imagination is a political anxiety concerning how to limit their potential effects. In light of Locke's views on education, Mehta concludes that the promise of liberation at the heart of liberalism is vitiated by its constraints on cognitive and political freedom. 410 0$aContestations. 606 $aIndividuality 606 $aImagination 606 $aAuthority 606 $aLiberty 608 $aElectronic books. 615 0$aIndividuality. 615 0$aImagination. 615 0$aAuthority. 615 0$aLiberty. 676 $a320/.01 700 $aMehta$b Uday Singh$0729996 702 $aen Book Program$b National Endowment for the Humanities Op$4aut$4http://id.loc.gov/vocabulary/relators/aut 712 02$aen Book Program 801 0$bMdBmJHUP 801 1$bMdBmJHUP 906 $aBOOK 912 $a9910272353203321 996 $aThe Anxiety of Freedom$92436950 997 $aUNINA LEADER 04450nam 2200445z- 450 001 9910220040403321 005 20210211 035 $a(CKB)3800000000216373 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/40834 035 $a(oapen)doab40834 035 $a(oapen)40834 035 $a(EXLCZ)993800000000216373 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAnatomy and Plasticity in Large-Scale Brain Models 210 $cFrontiers Media SA$d2017 215 $a1 online resource (173 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-065-1 330 $aSupercomputing facilities are becoming increasingly available for simulating activity dynamics in large-scale neuronal networks. On today's most advanced supercomputers, networks with up to a billion of neurons can be readily simulated. However, building biologically realistic, full-scale brain models requires more than just a huge number of neurons. In addition to network size, the detailed local and global anatomy of neuronal connections is of crucial importance. Moreover, anatomical connectivity is not fixed, but can rewire throughout life (structural plasticity)-an aspect that is missing in most current network models, in which plasticity is confined to changes in synaptic strength (synaptic plasticity). The papers in this Ebook, which may broadly be divided into three themes, aim to bring together high-performance computing with recent experimental and computational research in neuroanatomy. In the first theme (fiber connectivity), new methods are described for measuring and data-basing microscopic and macroscopic connectivity. In the second theme (structural plasticity), novel models are introduced that incorporate morphological plasticity and rewiring of anatomical connections. In the third theme (large-scale simulations), simulations of large-scale neuronal networks are presented with an emphasis on anatomical detail and plasticity mechanisms. Together, the articles in this Ebook make the reader aware of the methods and models by which large-scale brain networks running on supercomputers can be extended to include anatomical detail and plasticity.Supercomputing facilities are becoming increasingly available for simulating activity dynamics in large-scale neuronal networks. On today's most advanced supercomputers, networks with up to a billion of neurons can be readily simulated. However, building biologically realistic, full-scale brain models requires more than just a huge number of neurons. In addition to network size, the detailed local and global anatomy of neuronal connections is of crucial importance. Moreover, anatomical connectivity is not fixed, but can rewire throughout life (structural plasticity)-an aspect that is missing in most current network models, in which plasticity is confined to changes in synaptic strength (synaptic plasticity). The papers in this Ebook, which may broadly be divided into three themes, aim to bring together high-performance computing with recent experimental and computational research in neuroanatomy. In the first theme (fiber connectivity), new methods are described for measuring and data-basing microscopic and macroscopic connectivity. In the second theme (structural plasticity), novel models are introduced that incorporate morphological plasticity and rewiring of anatomical connections. In the third theme (large-scale simulations), simulations of large-scale neuronal networks are presented with an emphasis on anatomical detail and plasticity mechanisms. Together, the articles in this Ebook make the reader aware of the methods and models by which large-scale brain networks running on supercomputers can be extended to include anatomical detail and plasticity. 606 $aNeurosciences$2bicssc 610 $aAnatomy 610 $abrain models 610 $aconnectivity 610 $ahigh-performance computing 610 $asimulation 610 $astructural plasticity 610 $aSupercomputing 615 7$aNeurosciences 700 $aArjen van Ooyen$4auth$01353112 702 $aMarkus Butz$4auth 702 $aWolfram Schenck$4auth 906 $aBOOK 912 $a9910220040403321 996 $aAnatomy and Plasticity in Large-Scale Brain Models$93220458 997 $aUNINA