LEADER 03891nam 2200529 450 001 9910270899503321 005 20191022090648.0 010 $a1-119-14349-7 010 $a1-119-14347-0 010 $a1-119-14350-0 035 $a(CKB)4330000000008868 035 $a(Safari)9781119143468 035 $a(OCoLC)1031279370 035 $a(MiAaPQ)EBC5151462 035 $a(CaSebORM)9781119143468 035 $a(MiAaPQ)EBC7076134 035 $a(Au-PeEL)EBL7076134 035 $a(EXLCZ)994330000000008868 100 $a20171218h20182018 uy 0 101 0 $aeng 135 $aurunu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMultivalency $econcepts, research & applications /$fedited by Jurriaan Huskens [and three others] 205 $a1st edition 210 1$aHoboken, New Jersey :$cWiley,$d2018. 210 4$dİ2018 215 $a1 online resource (1 volume) $cillustrations 311 $a1-119-14346-2 320 $aIncludes bibliographical references at the end of each chapters and index. 330 $aConnects fundamental knowledge of multivalent interactions with current practice and state-of-the-art applications Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced researchers in the field. Multivalency: Concepts, Research & Applications is divided into three parts. Part one provides background knowledge on various aspects of multivalency and cooperativity and presents practical methods for their study. Fundamental aspects such as thermodynamics, kinetics and the principle of effective molarity are described, and characterisation methods, experimental methodologies and data treatment methods are also discussed. Parts two and three provide an overview of current systems in which multivalency plays an important role in chemistry and biology, with a focus on the design rules, underlying chemistry and the fundamental principles of multivalency. The systems covered range from chemical/materials-based ones such as dendrimers and sensors, to biological systems including cell recognition and protein binding. Examples and case studies from biochemistry/bioorganic chemistry as well as synthetic systems feature throughout the book. Introduces students and young scientists to the field of multivalent interactions and assists experienced researchers utilising the methodologies in their work Features examples and case studies from biochemistry/bioorganic chemistry, as well as synthetic systems throughout the book Edited by leading experts in the field with contributions from established scientists Multivalency: Concepts, Research & Applications is recommended for graduate students and junior scientists in supramolecular chemistry and related fields, looking for an introduction to multivalent interactions. It is also highly useful to experienced academics and scientists in industry working on research relating to multivalent and cooperative systems in supramolecular chemistry, organic chemistry, pharmaceutical chemistry, chemical biology, biochemistry, materials science and nanotechnology. 606 $aValence (Theoretical chemistry) 606 $aMultivalent molecules 608 $aElectronic books. 615 0$aValence (Theoretical chemistry) 615 0$aMultivalent molecules. 676 $a541.224 700 $aHuskens$b Jurriaan$01211231 702 $aHuskens$b Jurriaan$f1968- 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910270899503321 996 $aMultivalency$92795907 997 $aUNINA