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035   $a(CKB)4100000002484657
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/43699
035   $a(EXLCZ)994100000002484657
100   $a20202102d2017      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aComputational and Experimental Approaches in Multi-Target Pharmacology
210   $cFrontiers Media SA$d2017
215   $a1 electronic resource (122 p.)
225 1 $aFrontiers Research Topics
311   $a2-88945-252-2 
330   $aThe next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple targets, or combinations of drugs with compatible pharmacokinetics that work synergistically to maximize desirable effects while minimizing unwanted side effects. This e-Book contains ten original articles, each addressing a different aspect of this challenge. Together they open new perspectives and show the way forward in the development of multi-target therapeutics.
610   $asystems biology
610   $acomputer modeling
610   $adrug repurposing
610   $asynergy
610   $adrug discovery
610   $adrug combination
610   $ahigh throughput screening
610   $amultidrug therapeutics
610   $apolypharmacy
610   $amultifactorial process
700   $aThomas J. Anastasio$4auth$01279228
906   $aBOOK
912   $a9910261143503321
996   $aComputational and Experimental Approaches in Multi-Target Pharmacology$93014843
997   $aUNINA