LEADER 03203nam 2200433z- 450 001 9910261141003321 005 20210212 035 $a(CKB)4100000002484682 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/61903 035 $a(oapen)doab61903 035 $a(EXLCZ)994100000002484682 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aVentricular Mechanics in Congenital Heart Disease 210 $cFrontiers Media SA$d2017 215 $a1 online resource (120 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-264-6 330 $aLooking at "Horse in Motion", the iconic photograph by E. Muybridge, it is almost possible to hear the horse galloping. The pounding sound of the hoofs hitting the ground -like a drum- can also echo the rythmic beating of the human heart. That sound, that visceral rhythm, reminds us of the link between motion and performance: the perfectly executed stride of the horse, the incredible coordination of multiscale phenomena behind a heart beat. Furthermore, the decomposed sequence in Muybridge's photograph has become a well-known example of breaking motion into its components over time, and as such is reminiscent of those images that are routinely acquired in clinical practice, where the heart appears dilating and shirnking in a sequence of snapshots. The investigation of this motion and its subtleties is essential for refining our understanding of cardiac function, and the appreciation of how and when this motion is no longer perfectly executed can lead us to understand functional impairments and provide insight into the unfolding of pathology. In the presence of congenital heart disease (CHD), cardiac mechanics are altered: from single ventricle physiology to conduction abnormalities to different cardiomyopathies, it is important to both capture and interpret biomechanical changes that occur in the presence of a congenital defect. This special issue in Frontiers in Pediatrics, now an e-book, focuses on 'Ventricular mechanics in congenital heart disease' and looks at current knowledge of phenomena such as systolic/diastolic dysfuction and current methods (chiefly in cardiovascular magnetic resonance imaging and echocardiography) to evaluate cardiac function in the presence of CHD, and then presents a series of original studies that employ both medical imaging and computational modelling techniques to study specific CHD scenarios. 606 $aMedicine and Nursing$2bicssc 610 $acardiovascular magnetic resonance imaging 610 $acomputational modelling 610 $aCongenital Heart Diseases 610 $adiastolic function 610 $ahaemodynamics 610 $ahypoplastic left heart syndrome 610 $asystolic function 610 $aventricular mechanics 615 7$aMedicine and Nursing 700 $aGiovanni Biglino$4auth$01311263 702 $aAdelaide de Vecchi$4auth 906 $aBOOK 912 $a9910261141003321 996 $aVentricular Mechanics in Congenital Heart Disease$93030070 997 $aUNINA