LEADER 03472nam 2200481z- 450 001 9910261140203321 005 20210211 035 $a(CKB)4100000002484690 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54061 035 $a(oapen)doab54061 035 $a(EXLCZ)994100000002484690 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aA Multidisciplinary Look at Stenotrophomonas maltophilia: An Emerging Multi-Drug-Resistant Global Opportunistic Pathogen 210 $cFrontiers Media SA$d2017 215 $a1 online resource (133 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-353-7 330 $aStenotrophomonas maltophilia is a Gram-negative bacterium found in water, plant rhizospheres, animals, and foods. It is associated with a variety of infections in humans, involving respiratory tract (most common), soft tissue and bone, blood, eye, heart, and brain. This opportunistic pathogen is of serious concern to the immunocompromised patient population, and it is also being isolated with increasing frequency from the respiratory tract of individuals with cystic fibrosis. The observed increase worldwide in antibiotic resistance and the ability of this organism to make biofilms on epithelial cells and medical devices make it difficult for health-care personnel to treat infections caused by this pathogen. Recently, several genomes of S. maltophilia have been sequenced, revealing high genetic diversity among isolates. This pathogen uses a variety of molecular mechanisms to acquire and demonstrate resistance to an impressive array of antimicrobial drugs. Research has also focused on the pathogenesis of S. maltophilia in animal models and the resulting host immune response. S. maltophilia is recognized as an important organism in the plant microbiome. This environmental bacterium uses a diffusible signal mechanism for controlling its colonization and interaction with other bacteria and plants. S. maltophilia has also gained considerable research interest for its biotechnological applications, with recent studies on enzyme production, anti-biofilm strategies, biodegradation, and bioremediation. This e-book focuses on the latest developments in the areas of physiology, genomics, infection and immunity, host-pathogen interaction, pathogenesis, antimicrobial resistance and therapy, molecular epidemiology, applied and environmental microbiology, bioremediation and biotechnology. 517 $aMultidisciplinary Look at Stenotrophomonas maltophilia 517 $aA Multidisciplinary Look at Stenotrophomonas maltophilia 606 $aMicrobiology (non-medical)$2bicssc 610 $aantibiotic resistance mechanisms 610 $aantimicrobial activity 610 $abiocontrol 610 $abiofilms 610 $abioremediation 610 $acystic fibrosis 610 $airon 610 $aStenotrophomonas maltophilia 615 7$aMicrobiology (non-medical) 700 $aJoanna S. Brooke$4auth$01278168 702 $aGabriele Berg$4auth 702 $aGiovanni Di Bonaventura$4auth 702 $aJose-Luis Martinez$4auth 906 $aBOOK 912 $a9910261140203321 996 $aA Multidisciplinary Look at Stenotrophomonas maltophilia: An Emerging Multi-Drug-Resistant Global Opportunistic Pathogen$93012750 997 $aUNINA