LEADER 02236nam  2200469z- 450 
001 9910261140103321
005 20210212
035   $a(CKB)4100000002484691
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/62249
035   $a(oapen)doab62249
035   $a(EXLCZ)994100000002484691
100   $a20202102d2017      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aVirus Discovery by Metagenomics: The (Im)possibilities
210   $cFrontiers Media SA$d2017
215   $a1 online resource (216 p.)
225 1 $aFrontiers Research Topics
311 08$a2-88945-308-1 
330   $aSince the late 1800s, the discovery of new viruses was a gradual process. Viruses were described one by one using a suite of techniques such as (electron) microscopy and viral culture. Investigators were usually interested in a disease state within an organism, and expeditions in viral ecology were rare. The advent of metagenomics using high-throughput sequencing has revolutionized not only the rate of virus discovery, but also the nature of the discoveries. For example, the viral ecology and etiology of many human diseases are being characterized, non-pathogenic viral commensals are ubiquitous, and the description of environmental viromes is making progress. This Frontiers in Virology Research Topic showcases how metagenomic and bioinformatic approaches have been combined to discover, classify and characterize novel viruses.
517   $aVirus Discovery by Metagenomics
606   $aMicrobiology (non-medical)$2bicssc
610   $abacteriophages
610   $abioinformatics
610   $abiological dark matter
610   $ametagenome
610   $ametagenomics
610   $aphages
610   $avirome
610   $avirus discovery
615  7$aMicrobiology (non-medical)
700   $aKatrine L. Whiteson$4auth$01292330
702   $aAlejandro Reyes$4auth
702   $aRichard J. Hall$4auth
702   $aBas E. Dutilh$4auth
906   $aBOOK
912   $a9910261140103321
996   $aVirus Discovery by Metagenomics: The (Im)possibilities$93022179
997   $aUNINA