LEADER 01983nam  2200421z- 450 
001 9910261134303321
005 20231214133300.0
035   $a(CKB)4100000002484749
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53417
035   $a(EXLCZ)994100000002484749
100   $a20202102d2017      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aMicroenvironment-Derived Stem Cell Plasticity
210   $cFrontiers Media SA$d2017
215   $a1 electronic resource (114 p.)
225 1 $aFrontiers Research Topics
311   $a2-88945-344-8 
330   $aPlasticity is the hallmark of stem cells. At the same time, stem cells, like any other cell type, are influenced by their microenvironment and respond to it accordingly. A specific microenvironment is defined by a variety of factors, including biological and chemical factors, cell-cell interactions, but also metabolic and mechanical cues. Such dynamic and specialized microenvironment where the stem cells reside is considered a stem cell niche. Tissue injury as well as malignant tissue alterations lead to changes in the niche influencing the plasticity and biology of residing stem cells. Similarly, the niche changes upon tissue damage, which eventually induces differentiation of stem cells and ultimately regeneration of the tissue.
610   $amicroenvironment
610   $astem cells
610   $atissue regeneration
610   $aimmunomodulation
610   $aextracellular vesicles (EVs)
610   $aoxygen tension
610   $aplasticity
610   $aimaging
700   $aMarietta Herrmann$4auth$01331054
702   $aSlavko Mojsilovic$4auth
702   $aJelena Krstic$4auth
702   $aIvana Gadjanski$4auth
906   $aBOOK
912   $a9910261134303321
996   $aMicroenvironment-Derived Stem Cell Plasticity$93040079
997   $aUNINA