LEADER 03505nam 22005775 450 001 9910254658003321 005 20200706201156.0 010 $a3-319-53168-9 024 7 $a10.1007/978-3-319-53168-7 035 $a(CKB)3710000001388507 035 $a(DE-He213)978-3-319-53168-7 035 $a(MiAaPQ)EBC4863574 035 $a(PPN)201472090 035 $a(EXLCZ)993710000001388507 100 $a20170520d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCell Biology of Herpes Viruses /$fedited by Klaus Osterrieder 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (VII, 224 p. 18 illus., 9 illus. in color.) 225 1 $aAdvances in Anatomy, Embryology and Cell Biology,$x0301-5556 ;$v223 311 $a3-319-53167-0 320 $aIncludes bibliographical references at the end of each chapters. 327 $aInitial contact: The first steps in herpesvirus entry -- Herpesvirus capsid assembly and DNA packaging -- Interindividual spread of herpesviruses -- Innate immune mechanisms and herpes simplex virus infection and disease -- Herpesvirus latency. On the importance of positioning oneself -- The human CMV IE1 protein: An offender of PML nuclear bodies -- Assembly and egress of an alphaherpesvirus clockwork -- Herpes simplex virus membrane fusion. . 330 $aHerpes viruses are widely distributed in nature, causing disease in organisms as diverse as bivalves and primates, including humans. Each virus appears to have established a long-standing relationship with its host, and the viruses have the ability to manipulate and control the metabolism of host cells, as well as innate and adaptive antiviral immune responses. Herpes viruses maintain themselves within hosts in a latent state resulting in virus persistence for years ? usually for the life span of the hosts. Herpes viruses comprise a large number of pathogens with diverse cellular targets and biological consequences of infection. What they have in common is their structure and the fact that they establish a dormant (latent) infection in their hosts that usually persists for life. The reviews here will highlight the general principles of herpes virus infection, with equal attention to overall principle and important difference. Also, the cell type- and life-style dependent differences in the establishment and maintenance of virus persistence will be covered. 410 0$aAdvances in Anatomy, Embryology and Cell Biology,$x0301-5556 ;$v223 606 $aVirology 606 $aImmunology 606 $aCytology 606 $aVirology$3https://scigraph.springernature.com/ontologies/product-market-codes/B22003 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 615 0$aVirology. 615 0$aImmunology. 615 0$aCytology. 615 14$aVirology. 615 24$aImmunology. 615 24$aCell Biology. 676 $a576.6484 702 $aOsterrieder$b Klaus$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910254658003321 996 $aCell Biology of Herpes Viruses$91552000 997 $aUNINA