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010   $a3-662-53270-0
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035   $a(DE-He213)978-3-662-53270-6
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035   $a(EXLCZ)993710000001307006
100   $a20170504d2017      u|         0
101 0 $aeng
135   $aurnn#008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aPercutaneous Penetration Enhancers Drug Penetration Into/Through the Skin $eMethodology and General Considerations /$fedited by Nina Dragicevic, Howard I. Maibach
205   $a1st ed. 2017.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2017.
215   $a1 online resource (XVI, 414 p. 126 illus., 50 illus. in color.)
311 08$a3-662-53268-9 
320   $aIncludes bibliographical references and index.
327   $aAssessment Of Drug Penetration Enhancement -- Basic Mathematics -- Influence Of Occlusive Versus Non-Occlusive Application Conditions -- Finite Dose Versus Infinite Dose -- Prediction Of Skin Absorption From Complex Formulations -- Mechanistic Studies Of Permeation Enhancers -- High Throughput Screening -- Corneoxenometry -- Tape-Stripping -- Epr In Determing Drug Penetration -- Raman Spectroscopy -- Atr-Ftir -- Confocal Laser Scanning Microscopy -- The Use Of Skin Alternatives For Testing Percutaneous Penetration -- Human Native And Reconstructed Skin Preparations For In-Vitro Penetration And Permeations Studies -- Novel Approaches To The Design And Development Of Functional Human Skin -- The Retardation Of Percutaneous Penetration -- Retardation Strategies For Sunscreen Agents -- Military Perspectives In Chemical Penetration Retardation -- Patent Overview Of Penetration Enhancers -- Patent Overview Of Enhancement Techniques -- Safety And Ethics -- Research Ethics -- Current Status Of Dermal And TransdermalDrug Delivery.
330   $aPercutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods ? both well established and recently introduced ? in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered, and the latest findings are provided on skin structure and function, mathematics in skin permeation, and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners, students and dermatological scientists or dermatologists .
606   $aDermatology
606   $aPharmacology
606   $aDermatology
606   $aPharmacology
615  0$aDermatology.
615  0$aPharmacology.
615 14$aDermatology.
615 24$aPharmacology.
676   $a616.5
702   $aDragicevic$b Nina$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aMaibach$b Howard I.$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910254654303321
996   $aPercutaneous Penetration Enhancers Drug Penetration Into$91758009
997   $aUNINA