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010   $a3-319-56210-X
024 7 $a10.1007/978-3-319-56210-0
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035   $a(DE-He213)978-3-319-56210-0
035   $a(MiAaPQ)EBC4876545
035   $a(PPN)202993728
035   $a(EXLCZ)993710000001404663
100   $a20170612d2017      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aStroke Genetics /$fedited by Pankaj Sharma, James F. Meschia
205   $a2nd ed. 2017.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017.
215   $a1 online resource (XII, 431 p. 39 illus., 26 illus. in color.) 
311   $a3-319-56208-8 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aIntroduction -- Familial stroke epidemiology -- Association study results -- GWAS -- Aneurysms/carvernous/AVM -- ICH/amyloid/microbleeds -- CADASIL -- Fabry -- MELAS -- Sickle -- Other monogenic -- White matter disease -- Carotid atherosclerosis -- Dissection -- Pharmacogenomics -- Non-Caucasian stroke genetics -- Small vessel disease -- Genetics of neuroimaging in stroke -- Cerebrovenous thrombosis -- Ethics.
330   $aThis revised, expanded second edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genomewide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.
606   $aNeurology 
606   $aInternal medicine
606   $aHuman genetics
606   $aNeurology$3https://scigraph.springernature.com/ontologies/product-market-codes/H36001
606   $aInternal Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H33002
606   $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008
615  0$aNeurology .
615  0$aInternal medicine.
615  0$aHuman genetics.
615 14$aNeurology.
615 24$aInternal Medicine.
615 24$aHuman Genetics.
676   $a616.8
702   $aSharma$b Pankaj$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aMeschia$b James F$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910254651003321
996   $aStroke Genetics$91758813
997   $aUNINA