LEADER 03756nam 22005655 450 001 9910254633603321 005 20200629162257.0 010 $a3-658-13168-3 024 7 $a10.1007/978-3-658-13168-5 035 $a(CKB)3710000000718067 035 $a(DE-He213)978-3-658-13168-5 035 $a(MiAaPQ)EBC4534027 035 $a(PPN)194075974 035 $a(EXLCZ)993710000000718067 100 $a20160530d2016 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTowards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility $eExperiments and Monte Carlo Simulations /$fby Matthias Würl 205 $a1st ed. 2016. 210 1$aWiesbaden :$cSpringer Fachmedien Wiesbaden :$cImprint: Springer Spektrum,$d2016. 215 $a1 online resource (XV, 86 p. 30 illus., 10 illus. in color.) 225 1 $aBestMasters,$x2625-3577 311 $a3-658-13167-5 320 $aIncludes bibliographical references. 327 $aMonte Carlo Modeling of a Clinical Proton Beam -- Low-Dose Envelope and Field Size Factor -- PET Activation Studies. 330 $aMatthias Würl presents two essential steps to implement offline PET monitoring of proton dose delivery at a clinical facility, namely the setting up of an accurate Monte Carlo model of the clinical beamline and the experimental validation of positron emitter production cross-sections. In the first part, the field size dependence of the dose output is described for scanned proton beams. Both the Monte Carlo and an analytical computational beam model were able to accurately predict target dose, while the latter tends to overestimate dose in normal tissue. In the second part, the author presents PET measurements of different phantom materials, which were activated by the proton beam. The results indicate that for an irradiation with a high number of protons for the sake of good statistics, dead time losses of the PET scanner may become important and lead to an underestimation of positron-emitter production yields. Contents Monte Carlo Modeling of a Clinical Proton Beam Low-Dose Envelope and Field Size Factor PET Activation Studies Target Groups Researchers and students in the field of medical physics with focus on particle therapy Medical physicists at proton therapy facilities The Author Matthias Würl wrote his Master?s Thesis at the chair of Medical Physics at the Ludwig-Maximilians University Munich. He is now a PhD student at the same department, working on transmission imaging with laser-accelerated ions. 410 0$aBestMasters,$x2625-3577 606 $aNuclear physics 606 $aMathematical physics 606 $aBiophysics 606 $aBiophysics 606 $aParticle and Nuclear Physics$3https://scigraph.springernature.com/ontologies/product-market-codes/P23002 606 $aTheoretical, Mathematical and Computational Physics$3https://scigraph.springernature.com/ontologies/product-market-codes/P19005 606 $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008 615 0$aNuclear physics. 615 0$aMathematical physics. 615 0$aBiophysics. 615 0$aBiophysics. 615 14$aParticle and Nuclear Physics. 615 24$aTheoretical, Mathematical and Computational Physics. 615 24$aBiological and Medical Physics, Biophysics. 676 $a539.7 700 $aWürl$b Matthias$4aut$4http://id.loc.gov/vocabulary/relators/aut$0799797 906 $aBOOK 912 $a9910254633603321 996 $aTowards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility$92544878 997 $aUNINA