LEADER 04830nam 22008175 450 001 9910254612403321 005 20200629201121.0 010 $a3-319-24448-5 024 7 $a10.1007/978-3-319-24448-8 035 $a(CKB)3710000000539334 035 $a(EBL)4199792 035 $a(SSID)ssj0001597386 035 $a(PQKBManifestationID)16297982 035 $a(PQKBTitleCode)TC0001597386 035 $a(PQKBWorkID)14885665 035 $a(PQKB)11434607 035 $a(DE-He213)978-3-319-24448-8 035 $a(MiAaPQ)EBC4199792 035 $z(PPN)258850876 035 $a(PPN)190885483 035 $a(EXLCZ)993710000000539334 100 $a20151215d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aPhysical Models of Cell Motility /$fedited by Igor S. Aranson 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (208 p.) 225 1 $aBiological and Medical Physics, Biomedical Engineering,$x1618-7210 300 $aDescription based upon print version of record. 311 $a3-319-24446-9 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aIntroduction -- Phase-field Description of Cell Movement -- Role of Substrate Adhesiveness -- Cytoskeletal Waves -- Chemical Signaling -- Efficiency of Cell Motion. 330 $aThis book surveys the most recent advances in physics-inspired cell movement models. This synergetic, cross-disciplinary effort to increase the fidelity of computational algorithms will lead to a better understanding of the complex biomechanics of cell movement, and stimulate progress in research on related active matter systems, from suspensions of bacteria and synthetic swimmers to cell tissues and cytoskeleton.Cell motility and collective motion are among the most important themes in biology and statistical physics of out-of-equilibrium systems, and crucial for morphogenesis, wound healing, and immune response in eukaryotic organisms. It is also relevant for the development of effective treatment strategies for diseases such as cancer, and for the design of bioactive surfaces for cell sorting and manipulation. Substrate-based cell motility is, however, a very complex process as regulatory pathways and physical force generation mechanisms are intertwined. To understand the interplay between adhesion, force generation and motility, an abundance of computational models have been proposed in recent years, from finite element to immerse interface methods and phase field approaches. This book is primarily written for physicists, mathematical biologists and biomedical engineers working in this rapidly expanding field, and can serve as supplementary reading for advanced graduate courses in biophysics and mathematical biology. The e-book incorporates experimental and computer animations illustrating various aspects of cell movement. 410 0$aBiological and Medical Physics, Biomedical Engineering,$x1618-7210 606 $aBiophysics 606 $aBiological physics 606 $aBiomedical engineering 606 $aBioinformatics  606 $aComputational biology  606 $aPhysics 606 $aBiomathematics 606 $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aComputer Appl. in Life Sciences$3https://scigraph.springernature.com/ontologies/product-market-codes/L17004 606 $aNumerical and Computational Physics, Simulation$3https://scigraph.springernature.com/ontologies/product-market-codes/P19021 606 $aPhysiological, Cellular and Medical Topics$3https://scigraph.springernature.com/ontologies/product-market-codes/M31020 615 0$aBiophysics. 615 0$aBiological physics. 615 0$aBiomedical engineering. 615 0$aBioinformatics . 615 0$aComputational biology . 615 0$aPhysics. 615 0$aBiomathematics. 615 14$aBiological and Medical Physics, Biophysics. 615 24$aBiomedical Engineering and Bioengineering. 615 24$aComputer Appl. in Life Sciences. 615 24$aNumerical and Computational Physics, Simulation. 615 24$aPhysiological, Cellular and Medical Topics. 676 $a571.67 702 $aAranson$b Igor S$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910254612403321 996 $aPhysical Models of Cell Motility$91811762 997 $aUNINA