LEADER 03567nam 22006255 450 001 9910254609703321 005 20230810213626.0 010 $a3-658-11424-X 024 7 $a10.1007/978-3-658-11424-4 035 $a(CKB)3710000000515683 035 $a(EBL)4095879 035 $a(SSID)ssj0001584791 035 $a(PQKBManifestationID)16265239 035 $a(PQKBTitleCode)TC0001584791 035 $a(PQKBWorkID)14865140 035 $a(PQKB)11768888 035 $a(DE-He213)978-3-658-11424-4 035 $a(MiAaPQ)EBC4095879 035 $a(PPN)190526483 035 $a(EXLCZ)993710000000515683 100 $a20151116d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$a3D Analysis of the Myocardial Microstructure $eDetermination of Fiber and Sheet Orientations /$fby Johanna Maria Ticar 205 $a1st ed. 2016. 210 1$aWiesbaden :$cSpringer Fachmedien Wiesbaden :$cImprint: Springer Spektrum,$d2016. 215 $a1 online resource (86 p.) 225 1 $aBestMasters,$x2625-3615 300 $aDescription based upon print version of record. 311 $a3-658-11423-1 320 $aIncludes bibliographical references. 327 $aAcknowledgment; Contents; List of Figures; Abstract; Kurzfassung; 1 Introduction; 2 Materials and Methods; 2.1 Materials; 2.2 Methods; 2.2.1 Diffusion tensor imaging; 2.2.2 Multi-photon microscopy; 3 Results; 3.1 Diffusion tensor imaging; 3.2 Multi-photon microscopy; 3.2.1 Three-dimensional reconstruction and visualization; 3.2.2 Data analysis; 4 Discussion; 4.1 Diffusion tensor imaging; 4.2 Multi-photon microscopy; Bibliography 330 $aThe master thesis of Johanna Maria Ticar reveals high-resolution insights into the myocardial microstructure and illustrates that cardiac muscle fibers are straight, running in parallel with one preferred fiber direction, however, deposits such as fat seem to compromise the regular and compact structure. Second harmonic generation imaging combined with optical tissue clearing is an accurate method for determining the three-dimensional muscle fiber and sheet orientations and hence, allows the calculation of fiber rotation throughout the ventricle wall. Contents ? Structure of the Human Myocardium ? Imaging Tools for Fiber Mapping ? Optical Tissue Clearing ? Second Harmonic Generation Imaging ? 3D Reconstruction and Visualization Target Groups ? Researchers and Students in the field of Biomedical Engineering with a focus on Bioengineering and Biomechanics ? Professionals in the field of Biomedicine The Author Johanna Maria Ticar, MSc, studied Biomedical Engineering at Graz University of Technology. Her research interests are the microstructure of the human body, tissue engineering and regenerative medicine, foremost in the field of cardiology. 410 0$aBestMasters,$x2625-3615 606 $aBiophysics 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aBiophysics 606 $aBioanalysis and Bioimaging 606 $aBiomedical Research 615 0$aBiophysics. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 14$aBiophysics. 615 24$aBioanalysis and Bioimaging. 615 24$aBiomedical Research. 676 $a530 700 $aTicar$b Johanna Maria$4aut$4http://id.loc.gov/vocabulary/relators/aut$01065362 906 $aBOOK 912 $a9910254609703321 996 $a3D Analysis of the Myocardial Microstructure$92544837 997 $aUNINA