LEADER 05898nam 22007095 450 001 9910254586403321 005 20200630084329.0 010 $a3-662-55671-5 024 7 $a10.1007/978-3-662-55671-9 035 $a(CKB)4340000000223610 035 $a(DE-He213)978-3-662-55671-9 035 $a(MiAaPQ)EBC5592475 035 $a(PPN)221247114 035 $a(EXLCZ)994340000000223610 100 $a20171122d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTheoretical Molecular Biophysics /$fby Philipp O.J. Scherer, Sighart F. Fischer 205 $a2nd ed. 2017. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2017. 215 $a1 online resource (XVI, 513 p. 226 illus., 27 illus. in color.) 225 1 $aBiological and Medical Physics, Biomedical Engineering,$x1618-7210 311 $a3-662-55670-7 320 $aIncludes bibliographical references and index. 327 $aStatistical Mechanics of Biopolymers -- Protein Electrostatics and Solvation -- Reaction Kinetics -- Transport Processes -- Reaction Rate Theory -- Elementary Photophysics -- Elementary Photoinduced Processes -- Molecular Motor Models. 330 $aThis book gives an introduction to molecular biophysics. It starts from material properties at equilibrium related to polymers, dielectrics and membranes. Electronic spectra are developed for the understanding of elementary dynamic processes in photosynthesis including proton transfer and dynamics of molecular motors. Since the molecular structures of functional groups of bio-systems were resolved, it has become feasible to develop a theory based on the quantum theory and statistical physics with emphasis on the specifics of the high complexity of bio-systems. This introduction to molecular aspects of the field focuses on solvable models. Elementary biological processes provide as special challenge the presence of partial disorder in the structure which does not destroy the basic reproducibility of the processes. Apparently the elementary molecular processes are organized in a way to optimize the efficiency. Learning from nature by means exploring the relation between structure and function may even help to build better artificial solar cells. The reader is exposed to basic concepts in modern biophysics, such as entropic forces, phase separation, potential of mean force, electron and proton transfer, heterogeneous reactions, coherent and incoherent energy transfer as well as molecular motors. Basic knowledge in classical and Quantum mechanics, electrostatics and statistical physics is desirable. Simplified models are presented which can be solved in limited cases analytically from the guiding lines to generate the basis for a fundamental understanding of the more complex biophysical systems. Chapters close with challenging problems whose solutions are provided at the end of the book to complete the pedagogical treatment in the book. To the second edition several new chapters were added. The medium polarization is treated self-consistently using basic elements of polaron theory and more advanced nonlinear Schrödinger equations to describe the dynamics of solvation. Ion transport through a membrane was extended by the discussion of cooperative effects. Intramolecular transitions are now discussed in the new edition in much more detail, including also radiationless transitions. Very recent developments in spectroscopy are included, especially two-dimensional and hole-burning spectroscopy. The discussion of charge transfer processes was extended by including recent results of hole transfer in DNA in connection with the super-exchange mechanism. The chapter on molecular motors was rewritten to include the most recent developments of new models. The book is a useful text for students and researchers wanting to go through the mathematical derivations in the theories presented. This book attracts a group of applied mathematically oriented students and scholars to the exciting field of molecular biophysics. . 410 0$aBiological and Medical Physics, Biomedical Engineering,$x1618-7210 606 $aBiophysics 606 $aBiological physics 606 $aBiomathematics 606 $aBiomedical engineering 606 $aProteins  606 $aBiochemical engineering 606 $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008 606 $aMathematical and Computational Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/M31000 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aProtein Science$3https://scigraph.springernature.com/ontologies/product-market-codes/L14040 606 $aBiochemical Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/C12029 615 0$aBiophysics. 615 0$aBiological physics. 615 0$aBiomathematics. 615 0$aBiomedical engineering. 615 0$aProteins . 615 0$aBiochemical engineering. 615 14$aBiological and Medical Physics, Biophysics. 615 24$aMathematical and Computational Biology. 615 24$aBiomedical Engineering and Bioengineering. 615 24$aProtein Science. 615 24$aBiochemical Engineering. 676 $a572.8 700 $aScherer$b Philipp O.J$4aut$4http://id.loc.gov/vocabulary/relators/aut$0566029 702 $aFischer$b Sighart F$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910254586403321 996 $aTheoretical Molecular Biophysics$92000190 997 $aUNINA