LEADER 03738nam 22006615 450 001 9910254527403321 005 20260812171139.0 010 $a3-319-21434-9 024 7 $a10.1007/978-3-319-21434-4 035 $a(CKB)3710000000467552 035 $a(EBL)4178391 035 $a(SSID)ssj0001546639 035 $a(PQKBManifestationID)16141215 035 $a(PQKBTitleCode)TC0001546639 035 $a(PQKBWorkID)14796490 035 $a(PQKB)10271691 035 $a(DE-He213)978-3-319-21434-4 035 $a(MiAaPQ)EBC4178391 035 $a(PPN)188457844 035 $a(EXLCZ)993710000000467552 100 $a20150827d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAntiepileptic Drugs and Pregnancy $eA Guide for Prescribers /$fby MJ Eadie, FJE Vajda 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Adis,$d2016. 215 $a1 online resource (235 p.) 300 $aDescription based upon print version of record. 311 08$a3-319-21433-0 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $a1. Introduction -- 2. Antiepileptic drugs and becoming pregnant -- Part I. Antiepileptic Drug Pharmacokinetics in Pregnancy -- 3. Antiepileptic drug disposition and pregnancy -- 4. The older antiepileptic drugs -- 5. Commonly used newer antiepileptic drugs -- 6. Antiepileptic drugs sometimes used in pregnancy -- Part II. Antiepileptic Drugs and the Foetus -- 7. Antiepileptic drugs, epileptic seizures and the foetus -- 8. Antiepileptic drugs and foetal malformations - a possible class effect -- 9. Particular antiepileptic drugs and foetal malformations -- 10. Antiepileptic drugs, cognition and neurodevelopment -- Part III. Antiepileptic Drug use and Pregnancy -- 11. Antiepileptic drug therapy: management issues and pregnancy -- 12. Antiepileptic drugs and pregnancy – the future. 330 $aA description of our current understanding of antiepileptic drug use during pregnancy, this book includes chapters on the impact of seizures on the mother and developing child, changes in maternal physiology during pregnancy and its impact on drug disposition, and the pharmacokinetic differences between the various anti-seizure medications. It also deals with the possible harmful effects of antiepileptic drug exposure during pregnancy on the physical and intellectual development of the fetus. Clinicians have to balance the potential adverse effects of the medicine for the fetus and mother-to-be against the risks that uncontrolled seizures hold for both when treating pregnant women with antiepileptic drugs. Only recently have enough scientific data emerged to provide a rational basis for treatment decisions that take in both aspects. This work provides a single, accessible, and up-to-date resource for busy clinicians. 606 $aFamily medicine 606 $aMidwifery 606 $aGynecology 606 $aNeurology 606 $aGeneral Practice and Family Medicine 606 $aMidwifery 606 $aGynecology 606 $aNeurology 615 0$aFamily medicine. 615 0$aMidwifery. 615 0$aGynecology. 615 0$aNeurology. 615 14$aGeneral Practice and Family Medicine. 615 24$aMidwifery. 615 24$aGynecology. 615 24$aNeurology. 676 $a610 700 $aEadie$b Mervyn J.$4aut$4http://id.loc.gov/vocabulary/relators/aut$01147719 702 $aVajda$b FJE$4aut$4http://id.loc.gov/vocabulary/relators/aut 906 $aBOOK 912 $a9910254527403321 996 $aAntiepileptic Drugs and Pregnancy$93391958 997 $aUNINA