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100   $a20151218d2016      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aDescent of the Testis /$fby John M. Hutson, Jørgen Mogens Thorup, Spencer W. Beasley
205   $a2nd ed. 2016.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016.
215   $a1 online resource (188 p.)
300   $aDescription based upon print version of record.
311   $a3-319-25908-3 
320   $aIncludes bibliographical references at the end of each chapters.
327   $aIntroduction -- Evolution of Descent of the Testis and Early History of Research -- Transabdominal Migration of the Testis -- InguinoScrotal Descent of the Testis  -- Classification and Causes of Undescended Tested in Humans -- Cryptorchidism and Associated Anomalies -- The Postnatal Effects of Cryptorchidism -- Diagnosis of Undescended Testis -- Operative Treatment -- Hormonal Treatment -- Results of Treatment -- Conclusions and Future Development.
330   $aThis book provides a state of the art overview of all aspects of testicular descent and cryptorchidism, including the mechanisms of descent and the causes, consequences, diagnosis, and treatment of undescended testis. The advances in understanding that have been achieved over the past two decades are clearly explained, covering the latest genetic information on the causes of normal and abnormal testicular descent, the role of INSL3 in transabdominal migration, and the evidence that a neurotransmitter released from the genitofemoral nerve mediates androgenic control of inguinoscrotal descent. Exciting changes in the management of both congenital and acquired cryptorchidism, such as the widespread use of laparoscopy for impalpable testes inside the abdominal cavity, are fully described. Evidence for the benefits of orchidopexy within the first year of life is reviewed, and an individual chapter is also devoted to hormonal treatment. Throughout the book due attention is given to ongoing controversies and divergences of opinion. This new edition of Descent of the Testis will be a timely update and valuable reference for all who are involved in research into testicular descent and management of cryptorchidism.
606   $aPediatrics
606   $aHuman genetics
606   $aPediatric surgery
606   $aPediatrics$3https://scigraph.springernature.com/ontologies/product-market-codes/H49006
606   $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008
606   $aPediatric Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59079
615  0$aPediatrics.
615  0$aHuman genetics.
615  0$aPediatric surgery.
615 14$aPediatrics.
615 24$aHuman Genetics.
615 24$aPediatric Surgery.
676   $a610
700   $aHutson$b John M$4aut$4http://id.loc.gov/vocabulary/relators/aut$0943095
702   $aThorup$b Jørgen Mogens$4aut$4http://id.loc.gov/vocabulary/relators/aut
702   $aBeasley$b Spencer W$4aut$4http://id.loc.gov/vocabulary/relators/aut
906   $aBOOK
912   $a9910254514603321
996   $aDescent of the Testis$92498425
997   $aUNINA