LEADER 04288nam 22006855 450 001 9910254512703321 005 20200705230844.0 010 $a4-431-55732-6 024 7 $a10.1007/978-4-431-55732-6 035 $a(CKB)3710000000484672 035 $a(EBL)4179004 035 $a(SSID)ssj0001584900 035 $a(PQKBManifestationID)16265757 035 $a(PQKBTitleCode)TC0001584900 035 $a(PQKBWorkID)14865811 035 $a(PQKB)11019395 035 $a(DE-He213)978-4-431-55732-6 035 $a(MiAaPQ)EBC4179004 035 $a(PPN)190527447 035 $a(EXLCZ)993710000000484672 100 $a20150928d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBiological Effects of Fibrous and Particulate Substances /$fedited by Takemi Otsuki, Yasuo Yoshioka, Andrij Holian 205 $a1st ed. 2016. 210 1$aTokyo :$cSpringer Japan :$cImprint: Springer,$d2016. 215 $a1 online resource (229 p.) 225 1 $aCurrent Topics in Environmental Health and Preventive Medicine,$x2364-8333 300 $aDescription based upon print version of record. 311 $a4-431-55731-8 320 $aIncludes bibliographical references at the end of each chapters. 327 $a1. Macrophage and Multinucleated Giant Cell Classification -- 2. NLRP3 Inflammasome-Mediated Toxicity of Fibrous Particles -- 3. Approaching a Unified Theory for Particle-Induced Inflammation -- 4. Reproductive and Developmental Effects of Nanomaterials -- 5. Fibrogenic and Immunotoxic Responses to Carbon Nanotubes -- 6. Potential Hazards of Skin Exposure to Nanoparticles -- 7. Health Effects of Silver Nanoparticles and Silver Ions -- 8. Multiwalled Carbon Nanotube-Induced Pulmonary Fibrogenesis -- 9. Silicates and Autoimmunity -- 10. Asbestos Exposure and Autoimmunity -- 11. T Cell Alteration Caused by Exposure to Asbestos -- 12. Effects of Asbestos Fibers on Human Cytotoxic T Cells. 330 $a    This volume examines our current understanding of the biological effects of fibrous and particulate substances, including discussions on nanoparticles. It offers comprehensive information on the latest insights into the immunological effects of various irritants on the human body. Readers will benefit from the contributing authors? diverse perspectives and extensive discussions of key issues, which include molecular alterations of the immune system and autoimmune diseases in connection with asbestos and silica, among others. The chapters also discuss recommendations, practical methods, and nanosafety science in situations involving exposure to nanotoxic substances.     Edited in collaboration with the Japanese Society for Hygiene, this book provides up-to-date information on the immunological effects of nanotoxic substances to researchers interested in environmental and occupational health. Presenting a number of recent concepts and findings in the field, it enables readers to gain a comprehensive knowledge of health problems caused by environmental fibrous and particulate substances. 410 0$aCurrent Topics in Environmental Health and Preventive Medicine,$x2364-8333 606 $aPublic health 606 $aImmunology 606 $aPharmacology 606 $aPublic Health$3https://scigraph.springernature.com/ontologies/product-market-codes/H27002 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 615 0$aPublic health. 615 0$aImmunology. 615 0$aPharmacology. 615 14$aPublic Health. 615 24$aImmunology. 615 24$aPharmacology/Toxicology. 676 $a616.079 702 $aOtsuki$b Takemi$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aYoshioka$b Yasuo$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aHolian$b Andrij$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910254512703321 996 $aBiological Effects of Fibrous and Particulate Substances$92527147 997 $aUNINA