LEADER 03913nam 22006015 450 001 9910254505103321 005 20200629203346.0 010 $a3-319-23150-2 024 7 $a10.1007/978-3-319-23150-1 035 $a(CKB)3890000000002300 035 $a(EBL)4199767 035 $a(SSID)ssj0001597185 035 $a(PQKBManifestationID)16297161 035 $a(PQKBTitleCode)TC0001597185 035 $a(PQKBWorkID)14885486 035 $a(PQKB)11236403 035 $a(DE-He213)978-3-319-23150-1 035 $a(MiAaPQ)EBC4199767 035 $a(PPN)19088083X 035 $a(EXLCZ)993890000000002300 100 $a20151218d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBiologics to Treat Substance Use Disorders $eVaccines, Monoclonal Antibodies, and Enzymes /$fedited by Ivan D. Montoya 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (454 p.) 300 $aDescription based upon print version of record. 311 $a3-319-23149-9 320 $aIncludes bibliographical references and index. 327 $aIntroduction -- PART I: Vaccines: Introduction -- Nicotine -- Cocaine -- Heroin -- Metamphetamine -- PART II: Monoclonal antibodies: Introduction -- Cocaine -- Metamphetamine -- PCP -- PART III: Enzymes: Introduction -- Butyrylcholinesterase -- Cocaine Esterase -- PART IV: New strategies to optimize the development of biologics: Adenovirus based vaccines -- Nanotechnology based vaccines -- Protein Nanoparticles -- DNA Scaffolded Vaccines -- Single Hapten Conjugate Therapeutic Vaccine -- Vaccine Adjuvants -- Laser Adjuvant -- Peptide Conjugates & Cytokine Adjuvants -- T. brucei: A Platform for Immunization -- Vaccines for SUDs and HIV infection -- New Monoclonal Antibodies -- Protein Engineered for Controlled Duration of Action -- PART V: Ethical aspects of biologics to treat SUDs. 330 $aThis book is a scientific compendium documenting the state of the art in the discovery and development of vaccines, monoclonal antibodies, and enzymes for the treatment of Substance Use Disorders (SUDs). The book gives detailed consideration to some of the most cutting edge topics in addiction medicine, including vaccines for nicotine, cocaine, heroin, and methamphetamine dependence; monoclonal antibodies against cocaine, methamphetamine, and phencyclidine; and the enzymes butyrylcholinesterase and cocaine esterase. In addition, the text covers a wide range of new strategies designed to optimize the development and efficacy of biologics. Unlike any other resource, this book reviews how biologics offer exciting new therapeutic opportunities for various psychiatric conditions. Written by experts in the field, Biologics to Treat Substance Use Disorders is as an authoritative reference for psychiatrists, psychologists, and all other medical professionals working with patients suffering from Substance Use Disorders. 606 $aPsychopharmacology 606 $aPharmacotherapy 606 $aPharmacology 606 $aPsychopharmacology$3https://scigraph.springernature.com/ontologies/product-market-codes/H53010 606 $aPharmacotherapy$3https://scigraph.springernature.com/ontologies/product-market-codes/H69000 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 615 0$aPsychopharmacology. 615 0$aPharmacotherapy. 615 0$aPharmacology. 615 14$aPsychopharmacology. 615 24$aPharmacotherapy. 615 24$aPharmacology/Toxicology. 676 $a610 702 $aMontoya$b Ivan D$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910254505103321 996 $aBiologics to Treat Substance Use Disorders$92527138 997 $aUNINA