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001 9910254492703321
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010   $a3-662-47178-7
024 7 $a10.1007/978-3-662-47178-4
035   $a(CKB)4100000000882262
035   $a(DE-He213)978-3-662-47178-4
035   $a(MiAaPQ)EBC5100587
035   $a(PPN)220122083
035   $a(EXLCZ)994100000000882262
100   $a20171010d2017      u|             0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aCOPD$b[electronic resource] $eHeterogeneity and Personalized Treatment /$fedited by Sang-Do Lee
205   $a1st ed. 2017.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2017.
215   $a1 online resource (VIII, 341 p. 73 illus., 51 illus. in color.) 
311   $a3-662-47177-9 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aOverview -- Introduction: Summary -- Definition -- Epidemiology -- Risk Factors -- Pathology/Pathogenesis/Pathophysiology -- Assessment -- Introduction: Summary -- Symptoms: SGRQ, CAT, MRC -- Spirometry -- Images -- Biomarkers -- Comorbidity -- Heterogeneity -- Introduction: Summary -- Phenotypes of COPD -- Genetics -- Images -- ACOS -- Exacerbation -- Pulmonary Hypertension -- Management -- Introduction: Summary -- Prevention -- Pharmacologic -- Non-pharmacologic: LVR, Rehab, Nutritional support -- Management of exacerbation -- Management of Comorbidities -- Personalized Treatment: current practice and evidences from researches -- Prospective -- Cohort: KOLD, ANOLD; Big data, Network medicine.
330   $aThis book explains how analysis of the heterogeneity of chronic obstructive pulmonary disease (COPD) enhances understanding of the condition and leads to improved, personalized treatment. State of the art knowledge is presented on a range of issues related to the heterogeneity of COPD, such as phenotypes (clinical, physiologic, radiologic, etc.), genotypes, and the tools to be used for dissecting heterogeneity (CT, MRI, biomarkers, etc.). Especially modern radiologic imaging holds promise in this context, and its role is described in detail with the aid of numerous illustrations. The implications of the heterogeneity for personalized treatment are clearly identified, with description of an appropriate tailored treatment strategy for each subgroup of patients. Information is provided on both current and emerging strategies, including bronchoscopic lung volume reduction and approaches to the management of pulmonary hypertension and comorbidities. This book will be a great asset in clinical practice and research for all who have an interest in COPD, a leading cause of morbidity and mortality worldwide.
606   $aRespiratory organs?Diseases
606   $aPathology
606   $aRadiology
606   $aPneumology/Respiratory System$3https://scigraph.springernature.com/ontologies/product-market-codes/H33134
606   $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X
606   $aDiagnostic Radiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H29013
615  0$aRespiratory organs?Diseases.
615  0$aPathology.
615  0$aRadiology.
615 14$aPneumology/Respiratory System.
615 24$aPathology.
615 24$aDiagnostic Radiology.
676   $a616.2
702   $aLee$b Sang-Do$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910254492703321
996   $aCOPD$91556420
997   $aUNINA