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001 9910254476903321
005 20200705120617.0
010   $a4-431-56523-X
024 7 $a10.1007/978-4-431-56523-9
035   $a(CKB)3710000001186137
035   $a(DE-He213)978-4-431-56523-9
035   $a(MiAaPQ)EBC4850815
035   $a(PPN)200511289
035   $a(EXLCZ)993710000001186137
100   $a20170427d2017      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aAdult T-cell Leukemia/Lymphoma /$fedited by Toshiki Watanabe, Takuya Fukushima
205   $a1st ed. 2017.
210  1$aTokyo :$cSpringer Japan :$cImprint: Springer,$d2017.
215   $a1 online resource (VIII, 169 p. 41 illus., 26 illus. in color.) 
311   $a4-431-56521-3 
330   $aThis book provides essential information on the epidemiology, molecular and genetic features, anti-CCR4 antibody therapy and a nationwide study of transplantation on human T-leukemia virus type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare but important disease has restricted endemic areas and distinct clinical features such as a high frequency of hypercalcemia, strong predisposition to infection and poor response to chemotherapy, aspects which set ATL apart from other types of non-Hodgkin lymphoma. Given the small number of patients, enrollment in clinical trials has not been feasible, and establishing treatment standard has been difficult but new evidence, such as results of nationwide studies on transplantation, have shown new insights and potential treatments. Based on recent evidence, the book presents new treatment methods for ATL and infection prevention of HTLV-1, enabling clinicians, researchers and post-docs specializing in hematology and virology to gain a valuable overview of the disease.
606   $aHematology
606   $aOncology
606   $aInfectious diseases
606   $aImmunology
606   $aHematology$3https://scigraph.springernature.com/ontologies/product-market-codes/H3307X
606   $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160
606   $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096
606   $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000
615  0$aHematology.
615  0$aOncology.
615  0$aInfectious diseases.
615  0$aImmunology.
615 14$aHematology.
615 24$aOncology.
615 24$aInfectious Diseases.
615 24$aImmunology.
676   $a616.15
702   $aWatanabe$b Toshiki$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aFukushima$b Takuya$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910254476903321
996   $aAdult T-cell Leukemia$91551235
997   $aUNINA