LEADER 04459nam 22006015 450 001 9910254474003321 005 20200630135204.0 010 $a9783319435138 024 7 $a10.1007/978-3-319-43513-8 035 $a(CKB)3710000001072402 035 $a(DE-He213)978-3-319-43513-8 035 $a(MiAaPQ)EBC4810461 035 $a(PPN)198872283 035 $a(EXLCZ)993710000001072402 100 $a20170220d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSalivary Gland Development and Regeneration$b[electronic resource] $eAdvances in Research and Clinical Approaches to Functional Restoration /$fedited by Seunghee Cha 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (XIII, 263 p. 52 illus., 47 illus. in color.) 311 $a3-319-43511-6 311 $a3-319-43513-2 320 $aIncludes bibliographical references. 327 $aUpdates on Salivary Gland Development: Salivary Gland Development -- Systems Analysis of Salivary Gland Development and Disease -- The Roles of Mucins in Salivary Gland Development and Regeneration. Glandular Damage and Cell Replacement Therapy: Salivary Gland Resident Stem Cells -- Adult Stem Cells with Special Emphasis on Mesenchymal Stem Cells -- Cellular and Nuclear Reprogramming of Mesenchymal Stem Cells. Bioengineering of Salivary Glands: Current Cell Models for Bioengineering Salivary Glands -- 3D Organ Culture and Matrix Biology -- Clinical Application of 3D Printing Technology in Craniofacial Plastic Surgery and Salivary Gland Regeneration -- Functional Salivary Gland Regeneration by Organ Replacement Therapy -- Therapeutic Considerations for Functional Salivary Gland Restorations: Regulation of Salivary Secretion -- Gene Therapy in Experimental and Clinical Trials -- Surgical Approaches to Functional Restoration of Saliva Secretion. 330 $aThis book provides a comprehensive update on the latest information and knowledge which emerged from translational and basic science research endeavors, targeting the regeneration of salivary glands. The coverage includes salivary gland growth and development, stem cell therapy, bioengineering of salivary glands, and perspectives on and practical approaches to restoration of secretory function. More specifically, among the individual topics addressed are the various types of stem cell of value for cell replacement therapy, technological advances with respect to 3D printing, gene therapy, organ culture of salivary glands, and surgical aspects of the feasibility and practicality of transplantation. Readers will find helpful practical guidance on functional restorations of damaged salivary glands and stimulating insights into potential future directions in salivary gland regeneration research. The authors are all acknowledged experts from a range of academic and clinical backgrounds. Accordingly, the book will be of interest not only to clinicians, such as general dental practitioners, oral medicine specialists, and surgeons who manage dry mouth patients, but also to biomedical engineers, stem cell researchers, and transplant surgeons. 606 $aDentistry 606 $aOral surgery 606 $aMaxillofacial surgery 606 $aBiomedical engineering 606 $aStem cells 606 $aDentistry$3https://scigraph.springernature.com/ontologies/product-market-codes/D00009 606 $aOral and Maxillofacial Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59060 606 $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000 606 $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010 615 0$aDentistry. 615 0$aOral surgery. 615 0$aMaxillofacial surgery. 615 0$aBiomedical engineering. 615 0$aStem cells. 615 14$aDentistry. 615 24$aOral and Maxillofacial Surgery. 615 24$aBiomedical Engineering/Biotechnology. 615 24$aStem Cells. 676 $a617.6 702 $aCha$b Seunghee$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910254474003321 996 $aSalivary Gland Development and Regeneration$91757950 997 $aUNINA