LEADER 04055nam 22006015 450 001 9910254470003321 005 20200706002505.0 010 $a3-319-53235-9 024 7 $a10.1007/978-3-319-53235-6 035 $a(CKB)3710000001177755 035 $a(DE-He213)978-3-319-53235-6 035 $a(MiAaPQ)EBC4845066 035 $a(PPN)200512730 035 $a(EXLCZ)993710000001177755 100 $a20170421d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAdvances in Radiation Oncology /$fedited by Jeffrey Y.C. Wong, Timothy E. Schultheiss, Eric H. Radany 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (VIII, 271 p. 48 illus., 40 illus. in color.) 225 1 $aCancer Treatment and Research,$x0927-3042 311 $a3-319-53233-2 320 $aIncludes bibliographical references. 327 $aUse of Multi-parametric MRI in Radiotherapy -- MRI Guided Radiotherapy -- MRI Guided Focused Ultrasound and Thermal Oncology -- Use of PET and Novel Molecular Imaging in IGRT -- The Impact of IGRT on Normal Tissue Toxicity -- Image Guided Brachytherapy -- Hypofractionated IGRT for the treatment of primary cancers -- SBRT and the treatment of oligometastatic disease -- Molecular and image guided systemic targeted radiotherapy -- Integrating Radiotherapy and Immunotherapy -- Biomarkers and Radiotherapy -- Application of Mathematical and Systems Biology to Radiotherapy -- The Importance of Cancer Stem Cells in Radiotherapy -- Targeting DNA repair mechanisms in radiotherapy. . 330 $aThis book concisely reviews important advances in radiation oncology, providing practicing radiation oncologists with a fundamental understanding of each topic and an appreciation of its significance for the future of radiation oncology. It explores in detail the impact of newer imaging modalities, such as multiparametric magnetic resonance imaging (MRI) and positron emission tomography (PET) using fluorodeoxyglucose (FDG) and other novel agents, which deliver improved visualization of the physiologic and phenotypic features of a given cancer, helping oncologists to provide more targeted radiotherapy and assess the response. Due consideration is also given to how advanced technologies for radiation therapy delivery have created new treatment options for patients with localized and metastatic disease, highlighting the increasingly important role of image-guided radiotherapy in treating systemic and oligometastatic disease. Further topics include the potential value of radiotherapy in enhancing immunotherapy thanks to the broader immune-stimulatory effects, how cancer stem cells and the tumor microenvironment influence response, and the application of mathematical and systems biology methods to radiotherapy. 410 0$aCancer Treatment and Research,$x0927-3042 606 $aOncology   606 $aRadiotherapy 606 $aRadiology 606 $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160 606 $aRadiotherapy$3https://scigraph.springernature.com/ontologies/product-market-codes/H29056 606 $aDiagnostic Radiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H29013 615 0$aOncology  . 615 0$aRadiotherapy. 615 0$aRadiology. 615 14$aOncology. 615 24$aRadiotherapy. 615 24$aDiagnostic Radiology. 676 $a616.9940642 702 $aWong$b Jeffrey Y.C$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aSchultheiss$b Timothy E$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aRadany$b Eric H$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910254470003321 996 $aAdvances in Radiation Oncology$91551247 997 $aUNINA