LEADER 04401nam 22005295 450 001 9910254468903321 005 20200706094741.0 010 $a9789811032929 024 7 $a10.1007/978-981-10-3292-9 035 $a(CKB)3710000001083991 035 $a(DE-He213)978-981-10-3292-9 035 $a(MiAaPQ)EBC4816283 035 $a(PPN)199765383 035 $a(EXLCZ)993710000001083991 100 $a20170302d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe Plasticity of Skeletal Muscle $eFrom Molecular Mechanism to Clinical Applications /$fedited by Kunihiro Sakuma 205 $a1st ed. 2017. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2017. 215 $a1 online resource (IX, 292 p. 21 illus., 14 illus. in color.) 311 $a981-10-3291-2 311 $a981-10-3292-0 320 $aIncludes bibliographical references at the end of each chapters. 327 $aChapter 1. Pluripotent stem cells and skeletal muscle differentiation: challenges and immediate applications (Nuria Montserrat) -- Chapter 2. Role of the ubiquitin-proteasome pathway in skeletal muscle (Yasuo Kitajima) -- Chapter 3. Stem cell therapy in muscle degeneration (Maurilio Sampaolesi) -- Chapter 4. The autophagy-dependent signaling in skeletal muscle (Kunihiro Sakuma) -- Chapter 5. Cytokines in skeletal muscle growth and decay (Arkadiusz Orzechowski) -- Chapter 6. The role of ribosome biogenesis is skeletal muscle hypertrophy (John J. McCarthy) -- Chapter 7. Comprehensive approach to sarcopenia and cachexia treatment (Hidetaka Wakabayashi) -- Chapter 8. The functional role of PGC-1 in muscular adaptation (Aaron Russell) -- Chapter 9. Biological function of muscle-secreted proteins (Wataru Aoi) -- Chapter 10. Biological role of TRPC1 in myogenesis, regeneration and disease (Ella W. Yeung) -- Chapter 11. Redox Regulation of Mechanotransduction and Atrophy in Unloaded Skeletal Muscle (John M. Lawler) -- Chapter 12. Participation of AMPK in the control of skeletal muscle mass (Tatsuro Egawa) -- Chapter 13. Therapeutic potential of skeletal muscle plasticity in muscle diseases and conditions (Gordon S. Lynch). 330 $aThis book discusses recent advances and various topics in plasticity of skeletal muscle from the perspectives of morphology, biological function, and clinical applications. Skeletal muscle is a highly plastic organ to adapt to environmental various demands, appears to endocrine various myokines, which flow into blood to protect the recognizing function of brain and inhibit the appearance of several cancer tumorigenesis. The book deals with current stem-cell based, pharmacological, and nutritional therapies for muscle wasting (sarcopenia, cachexia, and muscular dystrophy). It also explains the roles of biological mediators such as PGC-1, transient receptor potential cation channels (TRPC), and AMPK in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome biogenesis, and redox regulation of mechanotransduction to modulate skeletal muscle mass are also covered. It is an essential resource for physicians, researchers, post-docs as well as graduate students in the field of sports science including rehabilitation therapy, exercise physiology, exercise biochemistry, and molecular biology dealing with skeletal muscle. 606 $aSports medicine 606 $aRehabilitation 606 $aBiomedical engineering 606 $aSports Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H58005 606 $aRehabilitation$3https://scigraph.springernature.com/ontologies/product-market-codes/H55006 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 615 0$aSports medicine. 615 0$aRehabilitation. 615 0$aBiomedical engineering. 615 14$aSports Medicine. 615 24$aRehabilitation. 615 24$aBiomedical Engineering and Bioengineering. 676 $a617.1027 702 $aSakuma$b Kunihiro$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910254468903321 996 $aThe Plasticity of Skeletal Muscle$92528933 997 $aUNINA