LEADER 04210nam 22006855 450 001 9910254324303321 005 20200706155208.0 010 $a3-319-54253-2 024 7 $a10.1007/978-3-319-54253-9 035 $a(CKB)3710000001109583 035 $a(DE-He213)978-3-319-54253-9 035 $a(MiAaPQ)EBC4822955 035 $a(PPN)199768153 035 $a(EXLCZ)993710000001109583 100 $a20170315d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aShort Pulse Laser Systems for Biomedical Applications /$fby Kunal Mitra, Stephanie Miller 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (VII, 49 p. 26 illus., 9 illus. in color.) 225 1 $aSpringerBriefs in Applied Sciences and Technology,$x2191-530X 311 $a3-319-54252-4 320 $aIncludes bibliographical references and index. 327 $aIntroduction -- Short Pulse Laser Imaging -- Short Pulse Laser Based Thermal Therapy -- Use of Nanoparticles to Optimize Short Pulse Laser Based Biomedical Applications. 330 $aThis book presents practical information on the clinical applications of short pulse laser systems and the techniques for optimizing these applications in a manner that will be relevant to a broad audience, including engineering and medical students as well as researchers, clinicians, and technicians. Short pulse laser systems are useful for both subsurface tissue imaging and laser induced thermal therapy (LITT), which hold great promise in cancer diagnostics and treatment. Such laser systems may be used alone or in combination with optically active nanoparticles specifically administered to the tissues of interest for enhanced contrast in imaging and precise heating during LITT. Mathematical and computational models of short pulse laser-tissue interactions that consider the transient radiative transport equation coupled with a bio-heat equation considering the initial transients of laser heating were developed to analyze the laser-tissue interaction during imaging and therapy. Experiments were first performed to characterize the tissue optical properties needed to optimize the dose for thermal therapy. Experiments were then performed on animal models to characterize the heat affected zone for LITT. The experimental measurements were also validated using the computational models. . 410 0$aSpringerBriefs in Applied Sciences and Technology,$x2191-530X 606 $aBiomedical engineering 606 $aLasers 606 $aPhotonics 606 $aCancer$xResearch 606 $aNanotechnology 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000 606 $aOptics, Lasers, Photonics, Optical Devices$3https://scigraph.springernature.com/ontologies/product-market-codes/P31030 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aNanotechnology and Microengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T18000 615 0$aBiomedical engineering. 615 0$aLasers. 615 0$aPhotonics. 615 0$aCancer$xResearch. 615 0$aNanotechnology. 615 14$aBiomedical Engineering and Bioengineering. 615 24$aBiomedical Engineering/Biotechnology. 615 24$aOptics, Lasers, Photonics, Optical Devices. 615 24$aCancer Research. 615 24$aNanotechnology and Microengineering. 676 $a621.366 700 $aMitra$b Kunal$4aut$4http://id.loc.gov/vocabulary/relators/aut$0886497 702 $aMiller$b Stephanie$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910254324303321 996 $aShort Pulse Laser Systems for Biomedical Applications$91979656 997 $aUNINA