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010   $a3-319-28308-1
024 7 $a10.1007/978-3-319-28308-1
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035   $a(EBL)4509023
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035   $a(PQKBManifestationID)16455500
035   $a(PQKBTitleCode)TC0001666091
035   $a(PQKBWorkID)15000558
035   $a(PQKB)11533774
035   $a(DE-He213)978-3-319-28308-1
035   $a(MiAaPQ)EBC4509023
035   $a(PPN)193446235
035   $a(EXLCZ)993710000000649151
100   $a20160418d2016      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aTrauma Induced Coagulopathy /$fedited by Eduardo Gonzalez, Hunter B. Moore, Ernest E. Moore
205   $a1st ed. 2016.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016.
215   $a1 online resource (611 p.)
300   $aDescription based upon print version of record.
311 08$a3-319-28306-5 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aCell-Mediated Hemostasis -- Antithrombin Contributions to Physiological Hemostasis and Thrombosis Prevention, and its Dysregulation in Trauma and TIC -- Physiology of Hemostasis: Plasmin-antiplasmin system -- Thrombin Formation -- Fibrinogen -- Activated Protein C -- Pathogenesis of Trauma Induced Coagulopathy: The Endothelium -- Platelets -- Fibrinolysis -- Neutrophils, Inflammation and Innate Immunity in Trauma-Induced Coagulopathy -- DAMPs: Damage-Associated Molecular Pattern Molecules in Hemostasis -- The Complement System and Coagulation -- Disseminated Intravascular Coagulation -- Prothrombin and Partial Thromboplastin Time -- Fibrinogen Assays -- Platelet Aggregometry -- Thrombelastography -- Rotational Thromboelastometry (ROTEM®) -- Red Blood Cell: Manufacture, Storage, and Transfusion -- Plasma Transfusion -- Cryoprecipitate Transfusion -- The Evolving Role of Platelets in Trauma Care -- Massive Transfusion Protocols -- Fibrinogen and Clotting Factor Replacement -- Anti-Fibrinolytics -- Venous Thromboembolism -- Congenital and Acquired Hypercoagulable States -- Coagulopathy in Traumatic Brain Injury (TBI) -- Liver Disease -- Hemostatic Abnormalities in Renal Disease -- Pediatrics -- Pregnancy -- Management of Chronically Anticoagulated Patients -- Animal Models -- .
330   $aThis text is aimed at defining the current concepts that define trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It will serve as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader will have full understanding of the tests that are used to study trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications are reviewed in detail. Trauma Induced Coagulopathy will also be a valuable source for quick reference to the clinician that is faced with specific clinical challenges when managing coagulopathy.
606   $aTraumatology
606   $aCritical care medicine
606   $aSurgery
606   $aAnesthesiology
606   $aTraumatic Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59125
606   $aIntensive / Critical Care Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H3100X
606   $aGeneral Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59044
606   $aAnesthesiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H13001
615  0$aTraumatology.
615  0$aCritical care medicine.
615  0$aSurgery.
615  0$aAnesthesiology.
615 14$aTraumatic Surgery.
615 24$aIntensive / Critical Care Medicine.
615 24$aGeneral Surgery.
615 24$aAnesthesiology.
676   $a610
702   $aGonzalez$b Eduardo$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aMoore$b Hunter B.$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aMoore$b Ernest E$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910254268503321
996   $aTrauma Induced Coagulopathy$92507351
997   $aUNINA