LEADER 04443nam 22006735 450 001 9910254264903321 005 20200703134439.0 010 $a3-319-24535-X 024 7 $a10.1007/978-3-319-24535-5 035 $a(CKB)3710000000636316 035 $a(EBL)4504075 035 $a(SSID)ssj0001665931 035 $a(PQKBManifestationID)16455307 035 $a(PQKBTitleCode)TC0001665931 035 $a(PQKBWorkID)15000056 035 $a(PQKB)10570189 035 $a(DE-He213)978-3-319-24535-5 035 $a(MiAaPQ)EBC4504075 035 $a(PPN)193445573 035 $a(EXLCZ)993710000000636316 100 $a20160409d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aConnective Tissue Disease $eA Comprehensive Guide - Volume 1 /$fedited by Dario Roccatello, Lorenzo Emmi 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (399 p.) 225 1 $aRare Diseases of the Immune System,$x2282-6505 300 $aDescription based upon print version of record. 311 $a3-319-24533-3 320 $aIncludes bibliographical references and index. 327 $aPart 1 Systemic Lupus Erythematosus -- Introduction - SLE in 21st Century -- Epidemiologic aspects of SLE -- Immunopathogenesis of SLE -- Clinical aspects in SLE -- Autoantibodies and biomarkers: diagnostic aspects -- Joint involvement in Systemic Lupus Erythematosus -- Cutaneous manifestations of SLE -- Kidney Involvement in SLE -- NPSLE -- Cardiovascular issues in SLE -- SLE and Pregnancy -- Vitamin D endocrine system and SLE -- The impact of aPL detection on pregnancy -- SLE and APS -- Disease activity indices and prognosis of SLE -- Conventional therapy for SLE -- Biological Therapy in SLE -- Part 2 Sjögren Syndrome -- Classification criteria for Sjögren syndrome -- Pathogenesis of Sjögren syndrome -- Autoantibodies in Sjögren syndrome and laboratory markers -- Parotid and Submandibular involvement in Sjögren syndrome -- Extraglandular involvement in Sjögren syndrome -- Dry eye in Sjögren syndrome: diagnostic tools and therapy -- Neurologic involvement in Sjögren syndrome -- Lymphoproliferative disorder in Sjögren syndrome -- Pathogenetic aspects of Sjogren Syndrome: Relationships with Cryoglobulinemia and Lymphoproliferation -- Systemic treatment of Sjögren syndrome. 330 $aIn this volume devoted to systemic lupus erythematosus (SLE) and Sjögren syndrome, leading specialists from different disciplines present the latest research findings on many aspects of the diseases and describe the most recent trends in treatment, such as the ?treat to target? approach. Both basic science and clinical medicine are addressed, with emphasis on the most promising clinical and laboratory-based studies. The coverage is comprehensive in scope, encompassing, for example, epidemiology, pathogenesis, autoantibodies and biomarkers, disease manifestations, involvement of different organs or systems, relationships with other disorders, biological therapy of SLE, and systemic treatment of Sjögren syndrome. Readers will find this first volume of Connective Tissue Disease to be an excellent source of information on the current understanding of, and clinical approach to, SLE and Sjögren syndrome that clearly conveys the progress made in recent years. 410 0$aRare Diseases of the Immune System,$x2282-6505 606 $aRheumatology 606 $aAntibodies 606 $aNephrology 606 $aRheumatology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33170 606 $aAntibodies$3https://scigraph.springernature.com/ontologies/product-market-codes/B14010 606 $aNephrology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33126 615 0$aRheumatology. 615 0$aAntibodies. 615 0$aNephrology. 615 14$aRheumatology. 615 24$aAntibodies. 615 24$aNephrology. 676 $a616.77 702 $aRoccatello$b Dario$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aEmmi$b Lorenzo$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910254264903321 996 $aConnective Tissue Disease$92513367 997 $aUNINA