LEADER 04415nam 22007095 450 001 9910254060403321 005 20200705094154.0 010 $a81-322-2680-1 024 7 $a10.1007/978-81-322-2680-2 035 $a(CKB)3710000000621832 035 $a(EBL)4456505 035 $a(SSID)ssj0001653999 035 $a(PQKBManifestationID)16433629 035 $a(PQKBTitleCode)TC0001653999 035 $a(PQKBWorkID)14983074 035 $a(PQKB)11465443 035 $a(DE-He213)978-81-322-2680-2 035 $a(MiAaPQ)EBC4456505 035 $a(PPN)192774689 035 $a(EXLCZ)993710000000621832 100 $a20160323d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBiology of C Reactive Protein in Health and Disease$b[electronic resource] /$fby Waliza Ansar, Shyamasree Ghosh 205 $a1st ed. 2016. 210 1$aNew Delhi :$cSpringer India :$cImprint: Springer,$d2016. 215 $a1 online resource (323 p.) 300 $aDescription based upon print version of record. 311 $a81-322-2678-X 320 $aIncludes bibliographical references. 327 $a1. Immune System: Freedom from the burden of diseases -- 2. CRP: Historical perspective, structure, evolution, synthesis, clinical and biological functions -- 3. Acute-Phase response and Acute Phase Proteins: Application in Human and Veterinary clinical chemistry -- 4. Inflammation, inflammatory diseases, markers and mediators: Role of CRP in some inflammatory diseases -- 5. Micro-heterogeneity of Proteins: Role in diseases -- 6. Pathobiological role of CRP in some diseases: Clinical medical applications of CRP -- 7. Role of CRP in cardiovascular diseases -- 8. Role of CRP in Leishmaniasis -- 9. CRP and diabetes: Sugar is not so sweet -- 10. CRP and Cancer -- 11. Role of CRP in Malaria. . 330 $aThis book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution.  Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, rheumatoid arthritis and infectious diseases and others. It also discusses the role of innate immunity and acute phase response (APR) and their key mediators in the host body in response to tissue injury, infection, trauma or surgery, immunological disorders or neoplastic growth. CRP?s significance in inflammation is highlighted, and its importance as a clinical marker in cardiovascular disease, its functional significance in Leishmania and Plasmodium infections, its association with the development of insulin resistance in type 2 diabetes mellitus, and its role in cancer are discussed in detail.  The book also includes clinical data studies and presents the latest research advances to further readers? understanding of CRP. . 606 $aHuman physiology 606 $aMolecular biology 606 $aBiotechnology 606 $aPlasma (Ionized gases) 606 $aForensic science 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 606 $aBiotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/C12002 606 $aPlasma Physics$3https://scigraph.springernature.com/ontologies/product-market-codes/P24040 606 $aForensic Science$3https://scigraph.springernature.com/ontologies/product-market-codes/B23000 615 0$aHuman physiology. 615 0$aMolecular biology. 615 0$aBiotechnology. 615 0$aPlasma (Ionized gases). 615 0$aForensic science. 615 14$aHuman Physiology. 615 24$aMolecular Medicine. 615 24$aBiotechnology. 615 24$aPlasma Physics. 615 24$aForensic Science. 676 $a610 700 $aAnsar$b Waliza$4aut$4http://id.loc.gov/vocabulary/relators/aut$01062339 702 $aGhosh$b Shyamasree$4aut$4http://id.loc.gov/vocabulary/relators/aut 906 $aBOOK 912 $a9910254060403321 996 $aBiology of C Reactive Protein in Health and Disease$92524452 997 $aUNINA