LEADER 03819nam  22006975  450 
001 9910254051003321
005 20200630105418.0
010   $a981-10-1486-8
024 7 $a10.1007/978-981-10-1486-4
035   $a(CKB)3710000000732526
035   $a(DE-He213)978-981-10-1486-4
035   $a(MiAaPQ)EBC4557281
035   $a(PPN)194376931
035   $a(EXLCZ)993710000000732526
100   $a20160614d2016      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aMechanism of Functional Expression of the Molecular Machines /$fby Masahiro Kinoshita
205   $a1st ed. 2016.
210  1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2016.
215   $a1 online resource (X, 70 p. 30 illus., 24 illus. in color.)
225 1 $aSpringerBriefs in Molecular Science,$x2191-5407
311   $a981-10-1484-1 
320   $aIncludes bibliographical references at the end of each chapters.
327   $aIntroduction -- Importance of Translational, Configurational Entropy of Water -- Molecular Machines -- Concluding Remarks: Mechanism of Functional Expression Common in the Molecular Machines.
330   $aThis brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules coexisting with the molecular machines in the entire system.
410  0$aSpringerBriefs in Molecular Science,$x2191-5407
606   $aPhysical chemistry
606   $aBiophysics
606   $aBiological physics
606   $aProteins 
606   $aStatistical physics
606   $aDynamical systems
606   $aPhysical Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C21001
606   $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008
606   $aProtein-Ligand Interactions$3https://scigraph.springernature.com/ontologies/product-market-codes/L14060
606   $aComplex Systems$3https://scigraph.springernature.com/ontologies/product-market-codes/P33000
606   $aStatistical Physics and Dynamical Systems$3https://scigraph.springernature.com/ontologies/product-market-codes/P19090
615  0$aPhysical chemistry.
615  0$aBiophysics.
615  0$aBiological physics.
615  0$aProteins .
615  0$aStatistical physics.
615  0$aDynamical systems.
615 14$aPhysical Chemistry.
615 24$aBiological and Medical Physics, Biophysics.
615 24$aProtein-Ligand Interactions.
615 24$aComplex Systems.
615 24$aStatistical Physics and Dynamical Systems.
676   $a539.6
700   $aKinoshita$b Masahiro$4aut$4http://id.loc.gov/vocabulary/relators/aut$01059440
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910254051003321
996   $aMechanism of Functional Expression of the Molecular Machines$92505873
997   $aUNINA