LEADER 04745nam 22006855 450 001 9910254024903321 005 20200705203016.0 010 $a3-319-31059-3 024 7 $a10.1007/978-3-319-31059-6 035 $a(CKB)3710000000636441 035 $a(EBL)4470930 035 $a(SSID)ssj0001665718 035 $a(PQKBManifestationID)16455466 035 $a(PQKBTitleCode)TC0001665718 035 $a(PQKBWorkID)15000526 035 $a(PQKB)11324649 035 $a(DE-He213)978-3-319-31059-6 035 $a(MiAaPQ)EBC4470930 035 $a(PPN)193444976 035 $a(EXLCZ)993710000000636441 100 $a20160402d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aManipulation of Multiphase Materials for Touch-less Nanobiotechnology $eA Pyrofluidic Platform /$fby Sara Coppola 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (121 p.) 225 1 $aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 300 $aDescription based upon print version of record. 311 $a3-319-31058-5 320 $aIncludes bibliographical references at the end of each chapters. 327 $aIntroduction -- Pyro-electric effect and polymers self-assembling -- Pyro-Electrohydrodynamic printing and multi jets Dispenser -- Pyro-EHD lithography, fabrication and employment of 3D microstructures -- High resolution patterning of biomaterials for tissue engineering -- Biodegradable microneedles for transdermal drug delivery -- Conclusions and perspectives. 330 $aThe thesis presents an original and smart way to manipulate liquid and polymeric materials using a ?pyro-fluidic platform? which exploits the pyro-electric effect activated onto a ferroelectric crystal. It describes a great variety of functionalities of the pyro-electrohydrodynamic platform, such as droplet self-assembling and dispensing, for manipulating multiphase liquids at the micro- and nanoscale. The thesis demonstrates the feasibility of non-contact self-assembling of liquids in plane (1D) using a micro engineered crystal, improving the dispensing capability and the smart transfer of material between two different planes (2D) and controlling and fabricating three-dimensional structures (3D). The thesis present the fabrication of highly integrated and automated ?lab-on-a-chip? systems based on microfluidics. The pyro-platform presented herein offers the great advantage of enabling the actuation of liquids in contact with a polar dielectric crystal through an electrode-less configuration. The simplicity and flexibility of the method for fabricating 3D polymer microstructures shows the great potential of the pyro-platform functionalities, exploitable in many fields, from optics to biosensing. In particular, this thesis reports the fabrication of optically active elements, such as nanodroplets, microlenses and microstructures, which have many potential applications in photonics. The capability for manipulating the samples of interest in a touch-less modality is very attractive for biological and chemical assays. Besides controlling cell growth and fate, smart micro-elements could deliver optical stimuli from and to cells monitoring their growth in real time, opening interesting perspectives for the realization of optically active scaffolds made of nanoengineered functional elements, thus paving the way to fascinating Optogenesis Studies. 410 0$aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 606 $aMaterials?Surfaces 606 $aThin films 606 $aNanotechnology 606 $aBiotechnology 606 $aSurfaces and Interfaces, Thin Films$3https://scigraph.springernature.com/ontologies/product-market-codes/Z19000 606 $aNanotechnology and Microengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T18000 606 $aMicroengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/C12040 615 0$aMaterials?Surfaces. 615 0$aThin films. 615 0$aNanotechnology. 615 0$aBiotechnology. 615 14$aSurfaces and Interfaces, Thin Films. 615 24$aNanotechnology and Microengineering. 615 24$aMicroengineering. 676 $a620.5 700 $aCoppola$b Sara$4aut$4http://id.loc.gov/vocabulary/relators/aut$01062347 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910254024903321 996 $aManipulation of Multiphase Materials for Touch-less Nanobiotechnology$92524467 997 $aUNINA