LEADER 04148nam 22006975 450 001 9910253956003321 005 20200705175559.0 010 $a3-319-66224-4 024 7 $a10.1007/978-3-319-66224-4 035 $a(CKB)4100000001382004 035 $a(DE-He213)978-3-319-66224-4 035 $a(MiAaPQ)EBC5210158 035 $a(PPN)222229683 035 $a(EXLCZ)994100000001382004 100 $a20171221d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPlatelets, Haemostasis and Inflammation /$fedited by Andreas Zirlik, Christoph Bode, Meinrad Gawaz 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (VIII, 292 p. 21 illus. in color.) 225 1 $aCardiac and Vascular Biology,$x2509-7830 ;$v5 311 $a3-319-66223-6 320 $aIncludes bibliographical references. 327 $aCardiac Imaging of Platelets and Inflammation -- Inflammation and Atherosclerosis -- Vaccination to Prevent Cardiovascular Disease -- Platelets as Regulators of Thrombosis and Inflammation -- Diversity of Inflammatory Cells in Vascular Degenerative Disease -- Platelet Inhibition as a Therapeutic Approach in Intravascular Intervention -- Diabetes, Thrombosis, and Cardiovascular Risks -- Therapeutic and Diagnostic Antibody Development -- Diabetes, Inflammation, and Platelets -- Platelet chemokines -- Platelet Signaling -- AMPs and Inflammation -- Platelets and Regeneration -- Platelets HMGB1 and cardiogenic schock -- Platelet cGMP and Vascular motion -- Platelet and Stroke -- Platelets and Polymorphisms. 330 $aThe book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosis, metabolic syndrome, diabetes, myocardial infarction, and other vascular pathologies. Particular focus is put on platelets as a link between haemostasis and inflammation contributing to both. Last but not least the books links the most recent advances in basic sciences with promising novel therapeutic applications and first results of clinical trials. The book is written for biomedical scientists in the sub disciplines vascular biology, biochemistry and immunology; and it as well will be of interest and value for academic physicians like cardiologists, hematologists, general internists and vascular surgeons. 410 0$aCardiac and Vascular Biology,$x2509-7830 ;$v5 606 $aBiomedical engineering 606 $aCardiovascular system 606 $aImmunology 606 $aCardiology 606 $aMolecular biology 606 $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000 606 $aCardiovascular Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16090 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aCardiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33037 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 615 0$aBiomedical engineering. 615 0$aCardiovascular system. 615 0$aImmunology. 615 0$aCardiology. 615 0$aMolecular biology. 615 14$aBiomedical Engineering/Biotechnology. 615 24$aCardiovascular Biology. 615 24$aImmunology. 615 24$aCardiology. 615 24$aMolecular Medicine. 676 $a612.117 702 $aZirlik$b Andreas$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aBode$b Christoph$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGawaz$b Meinrad$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253956003321 996 $aPlatelets, Haemostasis and Inflammation$92233548 997 $aUNINA