LEADER 03349nam  22005055  450 
001 9910253950503321
005 20200706105721.0
010   $a3-319-60189-X
024 7 $a10.1007/978-3-319-60189-2
035   $a(CKB)4100000000587448
035   $a(DE-He213)978-3-319-60189-2
035   $a(MiAaPQ)EBC5043118
035   $z(PPN)258860324
035   $a(PPN)204534836
035   $a(EXLCZ)994100000000587448
100   $a20170909d2017      u|         0
101 0 $aeng
135   $aurnn#008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aNeurotoxicity of Metals /$fedited by Michael Aschner, Lucio G. Costa
205   $a1st ed. 2017.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017.
215   $a1 online resource (VI, 383 p. 33 illus., 14 illus. in color.)
225 1 $aAdvances in Neurobiology,$x2190-5215 ;$v18
311   $a3-319-60188-1 
320   $aIncludes bibliographical references at the end of each chapters.
327   $aDevelopmental Neurotoxicity of Lead -- Manganese and developmental neurotoxicity -- Inherited disorders of manganese metabolism -- Chemical speciation of selenium and mercury as determinant of their neurotoxicity.- Metals and paraoxonases.- Manganese and the Insulin-IGF signaling network in Huntington?s disease and other neurodegenerative disorders.- Occupational Metal Exposure and Parkinsonism.- Inflammatory activation of microglia and astrocytes in manganese neurotoxicity.- Aluminum and Alzheimer?s disease.- Copper and Alzheimer?s Disease.- Uranium and the central nervous system: What should we learn from recent new tools and findings?.- Methylmercury-induced neurotoxicity: focus on pro oxidative events and related consequences.- Neurotoxicity of Vanadium -- Neurotoxicity of Zinc -- Neurotoxicity of Copper.- Thallium toxicity: general issues, neurological symptoms and neurotoxic mechanisms.- Neurodegeneration-induced by metals in Caenorhabditis elegans.          .
330   $aIn this book, international authorities address contemporary research in metal neurotoxicity. Essential and non-essential metals play an important role in neurodevelopmental and neurodegenerative diseases. Recent developments in understanding the role of metals in the etiology of these disorders have led to rapid growth in clarifying the pathology of some of the most devastating diseases we face and in identifying potential new therapies. Few books or periodicals have been wholly dedicated to the topic of metals, and this collection is intended to serve as a resource for all researchers interested in metals and their role in health and disease.
410  0$aAdvances in Neurobiology,$x2190-5215 ;$v18
606   $aNeurochemistry
606   $aNeurochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/B18010
615  0$aNeurochemistry.
615 14$aNeurochemistry.
676   $a615.9253
702   $aAschner$b Michael$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aCosta$b Lucio G$4edt$4http://id.loc.gov/vocabulary/relators/edt
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910253950503321
996   $aNeurotoxicity of Metals$92234094
997   $aUNINA