LEADER 06171nam 22006495 450 001 9910253937503321 005 20200702085308.0 010 $a981-10-3701-9 024 7 $a10.1007/978-981-10-3701-6 035 $a(CKB)4100000000587472 035 $a(DE-He213)978-981-10-3701-6 035 $a(MiAaPQ)EBC5051154 035 $a(PPN)204531829 035 $a(EXLCZ)994100000000587472 100 $a20170921d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aRegenerative Medicine: Laboratory to Clinic$b[electronic resource] /$fedited by Asok Mukhopadhyay 205 $a1st ed. 2017. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2017. 215 $a1 online resource (XIX, 537 p. 81 illus., 75 illus. in color.) 311 $a981-10-3700-0 320 $aIncludes bibliographical references and index. 327 $aPhysical forces that regulate stem cell fate -- Pluripotent stem cells: its potential applications -- Unraveling the role of long-non coding RNAs in pluripotent stem cells-based neuronal commitment and neurogenesis -- Control of quiescence in adult stem cells -- Etiology and treatment of osteoarthritis: A developmental biological perspective -- Differences in cell populations and expression of soluble mediators between normal wound healing and healing in the diabetic -- MSC-derived exosomes as tools in regenerative medicine -- Mixing of different batches of cells permits better therapeutic potential of MSCs -- Blood to blood: new candidate for regenerative medicine -- HSC based gene therapy for blood diseases -- Allogeneic stem cell transplantation including haplo-identical stem cell transplants -- Mesenchymal stem cells and transplantation tolerance -- Ideal stem cell candidate for regenerative medicine -- Pre-clinical/clinical study on idiopathic pulmonary fibrosis -- Comparative analysis between ES and iPS cells for use in regenerative medicine: scope, advantage and safety -- Regeneration of lacrimal gland: potential and progress -- Clinical trials in cardiac regeneration using adult stem cells: Current and future prospects -- Tissue engineering for the treatment of in large bone defect -- Corneal Regeneration: Current status and future directions -- Cell therapy for retinal regeneration: current progress and future challenges -- Vaculogenesis: Importance in regeneration of solid organs -- Cord blood banking in India and the global scenario -- Prospects and retrospect of clinical applications of stem cell in veterinary sciences -- Engineering of scaffolds for soft tissue engineering -- 3D bioprinting of tissue -- Tissue engineering: Cell, scaffold and growth factor based strategies -- Pre-clinical trial: A bottleneck that impedes development of regenerative medicine -- Stem cell research work ethics and Indian stem cell research policy. 330 $aThis book discusses the two different cellular approaches that are pursued in regenerative medicine: cell therapy and tissue engineering. It examines in detail the therapeutic application of hematopoietic stem cells in marrow regeneration, multi-potent mesenchymal stem cells (MSCs), also referred to as mesenchymal stromal cells. The interest in MSCs can be seen in more than 150 clinical trials, some of which have progressed to Phase III, despite the cells? limited differentiation potential. The book also explores how embryonic stem (ES) cells, being pluripotent in nature, can resolve some of the problems associated with adult stem cells, yet entail other challenges like risks of teratoma formation and immune rejection. A separate chapter deals with the role of noncoding RNAs in neuronal commitment of induced pluripotent stem (iPS) cells. Chapters like ?Cord blood banking in India and the global scenario?; ?3D bioprinting of tissue? and others will make this book an extremely interesting read for all students, researchers and clinicians working in the area of regenerative medicine/stem cells. The book is broadly divided into three parts, the first of which is devoted to basic information on stem cells and some aspect of disease biology, the second which addresses upcoming prospects in the regeneration of pancreas, liver, Lacrimal gland, and tissue engineering in general. Also, the second part discusses two important areas of translational regenerative medicine: challenges in pre-clinical study and manufacturing of cell based products. The third part covers bed side applications in the areas of orthopedic, eyes, hematology, dental tissue engineering, organ transplantation, control of aging, etc. . 606 $aRegenerative medicine 606 $aTissue engineering 606 $aLaboratory medicine 606 $aStem cells 606 $aBiomedical engineering 606 $aHuman physiology 606 $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080 606 $aLaboratory Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B15007 606 $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010 606 $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 615 0$aRegenerative medicine. 615 0$aTissue engineering. 615 0$aLaboratory medicine. 615 0$aStem cells. 615 0$aBiomedical engineering. 615 0$aHuman physiology. 615 14$aRegenerative Medicine/Tissue Engineering. 615 24$aLaboratory Medicine. 615 24$aStem Cells. 615 24$aBiomedical Engineering/Biotechnology. 615 24$aHuman Physiology. 676 $a612.028 676 $a571.538 702 $aMukhopadhyay$b Asok$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910253937503321 996 $aRegenerative Medicine: Laboratory to Clinic$92065511 997 $aUNINA