LEADER 04458nam 22006735 450 001 9910253936803321 005 20200703175340.0 010 $a981-10-6244-7 024 7 $a10.1007/978-981-10-6244-5 035 $a(CKB)4100000000587486 035 $a(DE-He213)978-981-10-6244-5 035 $a(MiAaPQ)EBC5061478 035 $z(PPN)258853204 035 $a(PPN)204531128 035 $a(EXLCZ)994100000000587486 100 $a20170927d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe Biophysics of Cell Membranes $eBiological Consequences /$fedited by Richard M. Epand, Jean-Marie Ruysschaert 205 $a1st ed. 2017. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2017. 215 $a1 online resource (VII, 219 p. 49 illus., 32 illus. in color.) 225 1 $aSpringer Series in Biophysics,$x0932-2353 ;$v19 311 $a981-10-6243-9 320 $aIncludes bibliographical references at the end of each chapters. 327 $aPreparation and Physical Properties of Asymmetric Model Membrane Vesicles -- Spontaneous lipid flip-flop in membranes: A still unsettled picture from experiments and simulations -- Membrane Lipid-Protein Interactions -- Principles of mechanosensing at the membrane interface -- Lipid domains and membrane (re)shaping: from biophysics to biology -- Minimal Cellular Models for Origins-of-Life Studies and Biotechnology. 330 $aThis volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well. 410 0$aSpringer Series in Biophysics,$x0932-2353 ;$v19 606 $aCell membranes  606 $aBiophysics 606 $aBiological physics 606 $aBioorganic chemistry 606 $aMedical genetics 606 $aMembrane Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16050 606 $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008 606 $aBioorganic Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C19010 606 $aGene Function$3https://scigraph.springernature.com/ontologies/product-market-codes/B12030 615 0$aCell membranes . 615 0$aBiophysics. 615 0$aBiological physics. 615 0$aBioorganic chemistry. 615 0$aMedical genetics. 615 14$aMembrane Biology. 615 24$aBiological and Medical Physics, Biophysics. 615 24$aBioorganic Chemistry. 615 24$aGene Function. 676 $a574.875 702 $aEpand$b Richard M$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aRuysschaert$b Jean-Marie$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253936803321 996 $aThe Biophysics of Cell Membranes$92264730 997 $aUNINA