LEADER 05041nam 22006255 450 001 9910253934603321 005 20200705074800.0 010 $a1-4939-7505-6 024 7 $a10.1007/978-1-4939-7505-1 035 $a(CKB)4340000000223150 035 $a(DE-He213)978-1-4939-7505-1 035 $a(MiAaPQ)EBC5153558 035 $a(PPN)221248668 035 $a(EXLCZ)994340000000223150 100 $a20171122d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe Biology of Mammalian Spermatogonia /$fedited by Jon M. Oatley, Michael D. Griswold 205 $a1st ed. 2017. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2017. 215 $a1 online resource (XI, 387 p. 44 illus., 41 illus. in color.) 311 $a1-4939-7503-X 320 $aIncludes bibliographical references and index. 327 $aPART 1: Spermatogenesis in Mammals -- Chapter 1: Organization of the Seminiferous Epithelium and the Cycle, and Morphometric Description of Spermatogonial Subtypes (Rodents and Primates) -- PART 2: Postnatal Development of the Spermatogonial Population -- Chapter 2: Transition of Prenatal Prospermatogonia to Postnatal Spermatogonia -- Chapter 3: Setting the Stage: The First Round of Spermatogenesis -- PART 3: Spermatogonial Stem Cells -- Chapter 4: Defining the Phenotype and Function of Mammalian Spermatogonial Stem Cells -- Chapter 5: The Biology of Mammalian Spermatogonia: Regulation of Spermatogonial Stem Cell Maintenance and Self-renewal -- PART 4: Spermatogonial Differentiation -- Chapter 6: Role of Retinoic Acid Signaling in the Differentiation of Spermatogonia -- Chapter 7: Gonadotropin and Steroid Hormone Control of Spermatogonial Differentiation -- PART 5: Genome Integrity of Spermatogonia -- Chapter 8: Frequency of Human Disease Mutations and Spermatogonial Stem Cell Function -- Chapter 9: The Spermatogonial Stem Cell and the Environment -- Chapter 10: Testicular Germ Cell Tumors and Teratomas -- PART 6: Tools to Study Spermatogonial Biology -- Chapter 11: Transplantation and Culture of Spermatogonial Stem Cells -- Chapter 12: In Vitro Differentiation of Spermatogonia -- PART 7: Therapeutic Potentials and Applications of Spermatogonia -- Chapter 13: Fertility Preservation in Cancer Patients -- Chapter 14: Application of Spermatogonial Transplantation in Agricultural Animals. . 330 $aThis book provides a resource of current understandings about various aspects of the biology of spermatogonia in mammals. Considering that covering the entire gamut of all things spermatogonia is a difficult task, specific topics were selected to provide foundational information that will be useful for seasoned researchers in the field of germ cell biology as well as investigators entering the area. Looking to the future, the editors predict that the foundational information provided in this book -- combined with the advent of new tools and budding interests in use of non-rodent mammalian models -- will produce another major advance in knowledge regarding the biology of spermatogonia over the next decade. In particular, we anticipate that the core molecular machinery driving different spermatogonial states in most, if not all, mammals will be described fully, the extrinsic signals emanating from somatic support cell populations to influence spermatogonial functions will become fully known, and the capacity to derive long-term cultures of SSCs and transplant the population to regenerate spermatogenesis and fertility will become a reality for higher order mammals. . 606 $aMolecular biology 606 $aAnimal physiology 606 $aCell biology 606 $aHuman physiology 606 $aReproductive medicine 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 606 $aAnimal Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L33030 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 606 $aReproductive Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H56002 615 0$aMolecular biology. 615 0$aAnimal physiology. 615 0$aCell biology. 615 0$aHuman physiology. 615 0$aReproductive medicine. 615 14$aMolecular Medicine. 615 24$aAnimal Physiology. 615 24$aCell Biology. 615 24$aHuman Physiology. 615 24$aReproductive Medicine. 676 $a611.01816 702 $aOatley$b Jon M$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGriswold$b Michael D$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910253934603321 996 $aThe Biology of Mammalian Spermatogonia$92184134 997 $aUNINA