LEADER 02911nam 22005295 450 001 9910253934403321 005 20200630164104.0 010 $a1-4939-7299-5 024 7 $a10.1007/978-1-4939-7299-9 035 $a(CKB)4100000001040729 035 $a(DE-He213)978-1-4939-7299-9 035 $a(MiAaPQ)EBC5143921 035 $a(PPN)221248374 035 $a(EXLCZ)994100000001040729 100 $a20171110d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGene and Cell Therapies for Beta-Globinopathies /$fedited by Punam Malik, John Tisdale 205 $a1st ed. 2017. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2017. 215 $a1 online resource (XII, 248 p. 16 illus., 12 illus. in color.) 225 1 $aAmerican Society of Gene & Cell Therapy,$x2626-7713 ;$v1013 311 $a1-4939-7297-9 320 $aIncludes bibliographical references and index. 330 $aThis book provides a comprehensive review of gene and cell therapy approaches for hemoglobinopathies. It covers the progress and current state of the field in hematopoietic stem cell transplantation for hemoglobinopathies and genetic correction of autologous hematopoietic stem cells. Chapters focus on such topics as the current standards of care and long term outcomes of b-thalassemias and sickle cell disease, the ability to generate autologous embryonic stem cell-like cells from primary somatic cells, and genetic strategies to reactivate fetal hemoglobin production. In addition to offering a thorough review of the field in its present state, this book also sheds light on the major changes expected in coming years.   Gene and Cell Therapies for Beta-Globinopathies is part of the American Society of Gene and Cell Therapy sub-series of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students, clinicians, and researchers interested in gene and cell therapy. 410 0$aAmerican Society of Gene & Cell Therapy,$x2626-7713 ;$v1013 606 $aGene therapy 606 $aCell biology 606 $aGene Therapy$3https://scigraph.springernature.com/ontologies/product-market-codes/B12020 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 615 0$aGene therapy. 615 0$aCell biology. 615 14$aGene Therapy. 615 24$aCell Biology. 676 $a616.151 702 $aMalik$b Punam$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aTisdale$b John$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253934403321 996 $aGene and Cell Therapies for Beta-Globinopathies$92234130 997 $aUNINA