LEADER 04608nam 22006735 450 001 9910253928903321 005 20200629200751.0 010 $a3-319-54090-4 024 7 $a10.1007/978-3-319-54090-0 035 $a(CKB)3710000001186113 035 $a(DE-He213)978-3-319-54090-0 035 $a(MiAaPQ)EBC4851700 035 $a(PPN)200512706 035 $a(EXLCZ)993710000001186113 100 $a20170428d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMacrophages$b[electronic resource] $eOrigin, Functions and Biointervention /$fedited by Malgorzata Kloc 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (X, 376 p. 37 illus., 27 illus. in color.) 225 1 $aResults and Problems in Cell Differentiation,$x0080-1844 ;$v62 311 $a3-319-54089-0 320 $aIncludes bibliographical references at the end of each chapters. 327 $aPart A. Evolution, origin and fate of macrophages -- 1 Evolutionary aspects of Macrophages polarization -- 2 Development and functional differentiation of tissue-resident vs. monocyte-derived macrophages in inflammatory reactions -- 3 Hofbauer cells ? placental macrophages of fetal origin -- 4 Mesenchymal stem cells direct the immunological fate of macrophages -- 5 Monocyte/Macrophage - NK cell Cooperation: Old Tools for New Functions -- 6 Macrophages in non-vertebrates: from insects and crustaceans to marine bivalves -- Part B. Immunobiology of macrophages -- 7 F4/80 as a Major Macrophage Marker: The case of the Peritoneum and Spleen -- 8 Immunobiology of Nitric Oxide and Regulation of Inducible Nitric Oxide Synthase -- 9 Role for mechanotransduction in macrophage and dendritic cell immunobiology -- Part C. Role of macrophages in disease -- 10 Macrophages? Role in Tissue Disease and Regeneration -- 11 Macrophages and their contribution to the development of atherosclerosis -- 12 Macrophage Dysfunction in Respiratory Disease -- Part D. Macrophages as a target for biointervention -- 13 Activation of macrophages in response to biomaterials -- 14 Macrophage differentiation in normal and accelerated wound healing -- 15 Macrophages and RhoA pathway in transplanted organs. . 330 $aThis volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important components of modern medicine. Macrophages are evolutionarily conserved phagocytotic cells. In recent years macrophages have emerged as one of the most versatile cells of immune system, which, depending on the milieu and circumstance, participate in development or inhibition of cancer, regeneration, wound healing, inflammation, organ rejection and interaction between mother and a fetus. This book will be of particular interest to researchers working in immunology, cancer research, developmental biology, or related fields. 410 0$aResults and Problems in Cell Differentiation,$x0080-1844 ;$v62 606 $aImmunology 606 $aDevelopmental biology 606 $aCancer research 606 $aMedical microbiology 606 $aBiomaterials 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aDevelopmental Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L18000 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003 606 $aBiomaterials$3https://scigraph.springernature.com/ontologies/product-market-codes/Z13000 615 0$aImmunology. 615 0$aDevelopmental biology. 615 0$aCancer research. 615 0$aMedical microbiology. 615 0$aBiomaterials. 615 14$aImmunology. 615 24$aDevelopmental Biology. 615 24$aCancer Research. 615 24$aMedical Microbiology. 615 24$aBiomaterials. 676 $a571.9685 702 $aKloc$b Malgorzata$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253928903321 996 $aMacrophages$92215784 997 $aUNINA