LEADER 03139nam 22004695 450 001 9910253927603321 005 20200703131918.0 010 $a3-319-52031-8 024 7 $a10.1007/978-3-319-52031-5 035 $a(CKB)3710000001140565 035 $a(DE-He213)978-3-319-52031-5 035 $a(MiAaPQ)EBC4835468 035 $a(PPN)200514458 035 $a(EXLCZ)993710000001140565 100 $a20170403d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAdipose Tissue Biology /$fedited by Michael E. Symonds 205 $a2nd ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (VI, 460 p. 40 illus., 28 illus. in color.) 311 $a3-319-52029-6 320 $aIncludes bibliographical references and index. 327 $aThe evolution of mammalian adipose tissue -- Adipocyte precursors: Developmental origins, self-renewal and plasticity -- Adipocyte differentiation -- Brown adipose tissue -- White adipose tissue -- Browning of white adipose tissue in humans: functional/clinical relevance -- Macrophages and inflammation -- Gender differences in adiposity -- Brown adipose tissue as a therapeutic target -- Dietary determinants of fat mass and body composition -- Genetic determinants of excess adiposity -- Early origins of obesity and developmental regulation of adiposity. . 330 $aThe past decade has seen an exponential increase in our knowledge and understanding of adipose tissue biology. This has coincided with the continued rise in obesity across all generations. Clearly despite substantial advances in research into adipose tissue this still has had limited impact on the on-going obesity epidemic across a majority of countries in the world. This book brings together many leading experts in the field to provide an up to date and comprehensive review of the key aspects of adipose tissue. It therefore includes chapters on evolution, development and inflammation together with a detailed review of brown and beige adipose tissue biology and their potential significance in preventing or combating obesity. These chapters are complemented by those on genetics and gender influences, together with nutrition through the life cycle. Ultimately the book provides an overview of the complexities of adipose tissue biology and the continuing challenge to combat obesity in the 21st century. 606 $aHuman physiology 606 $aNeurosciences 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 606 $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006 615 0$aHuman physiology. 615 0$aNeurosciences. 615 14$aHuman Physiology. 615 24$aNeurosciences. 676 $a612 702 $aSymonds$b Michael E$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910253927603321 996 $aAdipose Tissue Biology$92234125 997 $aUNINA