LEADER 03687nam 22006615 450 001 9910253923503321 005 20200704012957.0 010 $a9783319516172 024 7 $a10.1007/978-3-319-51617-2 035 $a(CKB)3710000001072444 035 $a(DE-He213)978-3-319-51617-2 035 $a(MiAaPQ)EBC4811129 035 $a(PPN)198870094 035 $a(EXLCZ)993710000001072444 100 $a20170221d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCartilage Regeneration /$fedited by Yunfeng Lin 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Humana,$d2017. 215 $a1 online resource (V, 97 p.) 225 1 $aStem Cell Biology and Regenerative Medicine,$x2196-8985 311 $a3-319-51616-7 311 $a3-319-51617-5 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aApplication of Stem Cells and the Factors Influence their Differentiation in Cartilage Tissue Engineering -- Application of Scaffold Materials in Cartilage Tissue Engineering -- Cellular Response to Surface Topography and Substrate Stiffness -- Electrospun Fibrous Scaffolds for Cartilage Tissue Regeneration -- The Research Advances of Nanomaterials Inducing Osteogenic and Chondrogenic Differentiation of Stem Cells. 330 $aThis book focuses on cartilage defects and new mesenchymal stem cell-based treatments for their repair and regeneration. Early chapters provide a review of current etiological findings and repair methods of cartilage defects. The next chapters discuss fundamental concepts and features of MSCs, including their proliferation, differentiation, migration and immunomodulatory effects. The discussion also includes clinical applications of MSCs in cartilage tissues, especially with regards to various animal models, biomaterials and transferring techniques. Cartilage Regeneration focuses on the biology of MSCs and their possible applications in cartilage reconstruction, with the goal of bringing new insights into regenerative medicine. It will be essential reading for researchers and clinicians in stem cells, regenerative medicine, biomedical engineering and orthopedic surgery. 410 0$aStem Cell Biology and Regenerative Medicine,$x2196-8985 606 $aStem cells 606 $aRegenerative medicine 606 $aTissue engineering 606 $aBiomedical engineering 606 $aOrthopedics 606 $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010 606 $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aSurgical Orthopedics$3https://scigraph.springernature.com/ontologies/product-market-codes/H45027 615 0$aStem cells. 615 0$aRegenerative medicine. 615 0$aTissue engineering. 615 0$aBiomedical engineering. 615 0$aOrthopedics. 615 14$aStem Cells. 615 24$aRegenerative Medicine/Tissue Engineering. 615 24$aBiomedical Engineering and Bioengineering. 615 24$aSurgical Orthopedics. 676 $a576 702 $aLin$b Yunfeng$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253923503321 996 $aCartilage Regeneration$92065495 997 $aUNINA