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001 9910253920303321
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010   $a981-10-2579-7
024 7 $a10.1007/978-981-10-2579-2
035   $a(CKB)4340000000062004
035   $a(MiAaPQ)EBC4901229
035   $a(DE-He213)978-981-10-2579-2
035   $a(PPN)203667344
035   $a(EXLCZ)994340000000062004
100   $a20170705d2017      u|             0
101 0 $aeng
135   $aurcnu||||||||
181   $2rdacontent
182   $2rdamedia
183   $2rdacarrier
200 10$aCancer and Chemoprevention: An Overview$b[electronic resource] /$fby Summya Rashid
205   $a1st ed. 2017.
210  1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2017.
215   $a1 online resource (173 pages) $cillustrations (some color), tables
311   $a981-10-2578-9 
320   $aIncludes bibliographical references at the end of each chapters.
327   $aIntroduction -- Hallmarks of Cancer -- Classification of Cancer -- Factors Influencing Cancer Development -- Carcinogenesis -- Molecular Mechanism of Carcinogenesis -- Oxidative Stress Induced Carcinogenesis -- Major Mediators Linking Inflammation and Cancer -- Apoptosis -- Chemoprevention -- Classification of Chemopreventive Agents -- Preclinical Development of Chemo Preventive Agents for Chemoprevention -- Modulation of Wnt/?-Catenin Signaling by Chemo Prevention -- Modulation of Akt/mTOR Pathway Signaling by Chemo Prevention -- Novel Chemopreventive Agents -- Chemoprevention by Resveratrol -- Chemoprevention by Genistein -- Chemoprevention by Apigenin -- Chemoprevention by Curcumin -- Chemoprevention by Fisetin -- Chemoprevention by Epigallocatechin-3-gallate (EGCG) -- Chemoprevention by Graviola -- Cancer Chemoprevention: Hurdles and Future Prospects and Considerations -- Clinical Trials of Chemoprevention -- Future of Chemoprevention.
330   $aThis book focuses on the most recent, relevant, comprehensive and significant advances in cancer and chemo prevention. It broadly discusses cancer, its hallmarks and classification, molecular mechanisms of outbreak, contributing factors, role of oxidative stress, inflammatory mediators and evading apoptosis, which leads to the progression of disease. Though modern medicine has left us with no option to treat this deadly disease due to drawbacks associated with conventional treatment ? like its non-targeted nature, drug resistance, varied organ toxicities and unaffordability ? chemoprevention offers a viable therapeutic window. Given chemoprevention?s importance in the present scenario, the book highlights various chemo preventive strategies currently used in the management of cancer; a selection of novel chemo preventive agents used at clinics and in the pre-clinical stage; hurdles to effective chemoprevention; future prospects and the road ahead. It offers a valuable guide for all graduate students and researchers seeking information on cancer and chemoprevention in general, irrespective of the specific type/pathways involved in its onset.
606   $aCancer research
606   $aApoptosis
606   $aGene expression
606   $aCell cycle
606   $aImmunology
606   $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001
606   $aApoptosis$3https://scigraph.springernature.com/ontologies/product-market-codes/L16060
606   $aGene Expression$3https://scigraph.springernature.com/ontologies/product-market-codes/B12010
606   $aCell Cycle Analysis$3https://scigraph.springernature.com/ontologies/product-market-codes/L16030
606   $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000
615  0$aCancer research.
615  0$aApoptosis.
615  0$aGene expression.
615  0$aCell cycle.
615  0$aImmunology.
615 14$aCancer Research.
615 24$aApoptosis.
615 24$aGene Expression.
615 24$aCell Cycle Analysis.
615 24$aImmunology.
676   $a616.99405
700   $aRashid$b Summya$4aut$4http://id.loc.gov/vocabulary/relators/aut$0979630
906   $aBOOK
912   $a9910253920303321
996   $aCancer and Chemoprevention: An Overview$92234119
997   $aUNINA